Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats

Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats

Viral infections of the CNS and their accompanying inflammation can cause long-term neurological effects, including increased risk for seizures. To examine the effects of CNS inflammation, we infused polyinosinic:polycytidylic acid, intracerebroventricularly to mimic a viral CNS infection in 14 day-...

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Bibliographic Details
Main Authors: M.A. Galic, K. Riazi, A.K. Henderson, S. Tsutsui, Q.J. Pittman
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Neurobiology of Disease
Subjects:
Seizure
Epilepsy
Infection
Inflammation
Virus
Cytokine
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002058

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