Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
Fever is a defence mechanism against infection, but it may also cause abnormal heart rhythm viaunknown mechanism. Here the authors identify FHF2 protein as a key regulator of myocardial excitability that protects the heart against conduction failure in response to an increase in body temperature.
Main Authors: | David S. Park, Akshay Shekhar, Christopher Marra, Xianming Lin, Carolina Vasquez, Sergio Solinas, Kevin Kelley, Gregory Morley, Mitchell Goldfarb, Glenn I. Fishman |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12966 |
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