β-defensins: An innate defense for bovine mastitis
Immune challenges are inevitable for livestock that are exposed to a varied range of adverse conditions ranging from environmental to pathogenic stresses. The β-defensins are antimicrobial peptides, belonging to "defensin" family and therefore acts as the first line of defense against the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Veterinary World
2017-08-01
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| Series: | Veterinary World |
| Subjects: | |
| Online Access: | http://www.veterinaryworld.org/Vol.10/August-2017/26.pdf |
| _version_ | 1819132281388793856 |
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| author | Ankita Gurao Sudhir Kumar Kashyap Ravinder Singh |
| author_facet | Ankita Gurao Sudhir Kumar Kashyap Ravinder Singh |
| author_sort | Ankita Gurao |
| collection | DOAJ |
| description | Immune challenges are inevitable for livestock that are exposed to a varied range of adverse conditions ranging from environmental to pathogenic stresses. The β-defensins are antimicrobial peptides, belonging to "defensin" family and therefore acts as the first line of defense against the major infections occurring in dairy cattle including intramammary infections. The better resistance to mastitis displayed by Bos indicus is implicit in the fact that they have better adapted and also has more sequence variation with rare allele conserved due to lesser artificial selection pressure than that of Bos taurus. Among the 58 in silico predicted β-defensins, only a few have been studied in the aspect of intramammary infections. The data on polymorphisms occurring in various β-defensin genes is limited in B. indicus, indicating toward higher possibilities for exploring marker for mastitis resistance. The following review shall focus on concisely summarizing the up-to-date research on β-defensins in B. taurus and discuss the possible scope for research in B. indicus. |
| first_indexed | 2024-12-22T09:28:54Z |
| format | Article |
| id | doaj.art-dbdc5070780640b4a26dda23f4abe7ac |
| institution | Directory Open Access Journal |
| issn | 0972-8988 2231-0916 |
| language | English |
| last_indexed | 2024-12-22T09:28:54Z |
| publishDate | 2017-08-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj.art-dbdc5070780640b4a26dda23f4abe7ac2022-12-21T18:31:01ZengVeterinary WorldVeterinary World0972-89882231-09162017-08-0110899099810.14202/vetworld.2017.990-998β-defensins: An innate defense for bovine mastitisAnkita Gurao0Sudhir Kumar Kashyap1Ravinder Singh2Department of Veterinary Microbiology and Biotechnology, College of Veterinary and Animal Sciences, Rajasthan University for Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.Department of Veterinary Microbiology and Biotechnology, College of Veterinary and Animal Sciences, Rajasthan University for Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.Department of Biotechnology, Sri Guru Granth Sahib World University, Fatehgarh Sahib - 140 407, Punjab, India.Immune challenges are inevitable for livestock that are exposed to a varied range of adverse conditions ranging from environmental to pathogenic stresses. The β-defensins are antimicrobial peptides, belonging to "defensin" family and therefore acts as the first line of defense against the major infections occurring in dairy cattle including intramammary infections. The better resistance to mastitis displayed by Bos indicus is implicit in the fact that they have better adapted and also has more sequence variation with rare allele conserved due to lesser artificial selection pressure than that of Bos taurus. Among the 58 in silico predicted β-defensins, only a few have been studied in the aspect of intramammary infections. The data on polymorphisms occurring in various β-defensin genes is limited in B. indicus, indicating toward higher possibilities for exploring marker for mastitis resistance. The following review shall focus on concisely summarizing the up-to-date research on β-defensins in B. taurus and discuss the possible scope for research in B. indicus.http://www.veterinaryworld.org/Vol.10/August-2017/26.pdfBos indicusβ-defensinsmastitis |
| spellingShingle | Ankita Gurao Sudhir Kumar Kashyap Ravinder Singh β-defensins: An innate defense for bovine mastitis Veterinary World Bos indicus β-defensins mastitis |
| title | β-defensins: An innate defense for bovine mastitis |
| title_full | β-defensins: An innate defense for bovine mastitis |
| title_fullStr | β-defensins: An innate defense for bovine mastitis |
| title_full_unstemmed | β-defensins: An innate defense for bovine mastitis |
| title_short | β-defensins: An innate defense for bovine mastitis |
| title_sort | β defensins an innate defense for bovine mastitis |
| topic | Bos indicus β-defensins mastitis |
| url | http://www.veterinaryworld.org/Vol.10/August-2017/26.pdf |
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