Chronic Hepatitis C Virus Infection Impairs M1 Macrophage Differentiation and Contributes to CD8<sup>+</sup> T-Cell Dysfunction
Chronic hepatitis C virus (HCV) infection causes generalized CD8<sup>+</sup> T cell impairment, not limited to HCV-specific CD8<sup>+</sup> T-cells. Liver-infiltrating monocyte-derived macrophages (MDMs) contribute to the local micro-environment and can interact with and infl...
| Main Authors: | , , , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
MDPI AG
2019-04-01
|
| 丛编: | Cells |
| 主题: | |
| 在线阅读: | https://www.mdpi.com/2073-4409/8/4/374 |