Differential contribution of p300 and CBP to regulatory element acetylation in mESCs
Abstract Background The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters. Although in most cases, CBP and p300 are considered to be fun...
| Главные авторы: | , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
BMC
2020-07-01
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| Серии: | BMC Molecular and Cell Biology |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s12860-020-00296-9 |