Spatially Fractionated Radiation Therapy in Sarcomas: A Large Single-Institution Experience

Spatially Fractionated Radiation Therapy in Sarcomas: A Large Single-Institution Experience

Purpose: Spatially fractionated radiation therapy (SFRT) is a recognized technique for enhancing tumor response in radioresistant and bulky tumors. We analyzed clinical and treatment outcomes in patients with bone and soft tissue sarcomas treated with modern SFRT techniques. Methods and Materials: P...

Full description

Bibliographic Details
Main Authors:	Safia K. Ahmed, MD, Ivy A. Petersen, MD, Michael P. Grams, PhD, Randi R. Finley, CMD, Michael G. Haddock, MD, Dawn Owen, MD, PhD
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Series:	Advances in Radiation Oncology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452109423002294

Similar Items

Spatially fractionated stereotactic body radiation therapy (Lattice) for large tumors
by: Sai Duriseti, MD, PhD, et al.
Published: (2021-05-01)

Early Experience Using Proton Beam Therapy for Extremity Soft Tissue Sarcoma: A Multicenter Study
by: Brady S. Laughlin, MD, et al.
Published: (2022-05-01)

Response to Central Boost Radiation Therapy in Unresectable Retroperitoneal Sarcoma: A Case Series
by: Danielle N. Burner, BS, et al.
Published: (2025-02-01)

Notable Response of SMARCA4-Deficient Undifferentiated Uterine Sarcoma to Palliative Radiation Therapy
by: Mariko Kurokawa, MD, et al.
Published: (2021-09-01)

Novel Postoperative Hypofractionated Accelerated Radiation Dose-Painting Approach for Soft Tissue Sarcoma
by: Matthew Mills, MD, et al.
Published: (2024-03-01)

Comprehensive Analysis of Treatment Approaches in Chest Wall Ewing Sarcoma: The Impact of Tumor Volume on Oncologic Outcomes
by: Brady S. Laughlin, MD, et al.
Published: (2025-04-01)

Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade
by: Tara Davidson, MD, et al.
Published: (2022-07-01)

Pembrolizumab After Carbon Ion Radiation Therapy for Alveolar Soft Part Sarcoma Shows a Remarkable Abscopal Effect: A Case Report
by: Masahiko Okamoto, MD, PhD, et al.
Published: (2022-05-01)

Complete Resection of Mediastinal Undifferentiated Pleomorphic Sarcoma
by: Ryusuke Sumiya, MD, PhD, et al.
Published: (2025-03-01)

Comparing Ultra-hypofractionated Proton versus Photon Therapy in Extremity Soft Tissue Sarcoma
by: Rehema Thomas, MD, et al.
Published: (2023-01-01)

Definitive Radiotherapy in the Management of Non-Resectable or Residual Retroperitoneal Sarcomas: Institutional Cohort Analysis and Systematic Review
by: Aleksandra Sobiborowicz, et al.
Published: (2021-02-01)

Spatially Fractionated Radiation Therapy for Palliation in Patients With Large Cancers: A Retrospective Study
by: Federico Iori, MD, et al.
Published: (2025-01-01)

Alveolar soft part sarcoma of the orbit: A case report
by: Takeshi Oda, MD, et al.
Published: (2021-12-01)

Association of Histologic Subtype With Radiation Response and Survival Outcomes in Synovial Sarcoma
by: Jennifer K. Matsui, MD, PhD, et al.
Published: (2025-03-01)

Lymphocyte Depletion Rate as a Biomarker of Radiation Dose to Circulating Lymphocytes During Fractionated Partial-Body Radiation Therapy
by: Susannah G. Ellsworth, MD, et al.
Published: (2022-09-01)

Pulmonary lymphatic involvement in metastatic uterine sarcomas: imaging and pathological appearance
by: Takahiro Kitayama, MD, et al.
Published: (2021-09-01)

Hypofractionated Radiation Therapy for Unresectable or Metastatic Sarcoma Lesions
by: David Boyce-Fappiano, MD, MHM, et al.
Published: (2022-05-01)

Clinical Experience With Machine Learning-Based Automated Treatment Planning for Whole Breast Radiation Therapy
by: Sua Yoo, PhD, et al.
Published: (2021-03-01)

Radiation-induced Sarcoma in the Head and Neck: Clinical, Imaging, Histopathological, and Therapeutic Characterization
by: Wilber Edison Bernaola-Paredes, DDS, OMS, MSc, PhD, et al.
Published: (2022-07-01)

Function-preserving Surgery for Femoral Sarcoma by “In Situ Preparation” Technique with a Free Flap
by: Kazuhisa Uemura, MD, et al.
Published: (2021-02-01)

An International Consensus on the Design of Prospective Clinical–Translational Trials in Spatially Fractionated Radiation Therapy
by: Nina A. Mayr, MD, et al.
Published: (2022-03-01)

A rare case of Ewing's sarcoma of the maxillary sinus
by: Amine Cherraqi, MD, et al.
Published: (2023-12-01)

Fractionated stereotactic radiation therapy for intact brain metastases
by: Samuel R. Marcrom, MD, et al.
Published: (2017-10-01)

Novel Definitive Hypofractionated Accelerated Radiation Dose-painting (HARD) for Unresected Soft Tissue Sarcomas
by: John Michael Bryant, MD, et al.
Published: (2024-04-01)

Effect of Target Changes on Target Coverage and Dose to the Normal Brain in Fractionated Stereotactic Radiation Therapy for Metastatic Brain Tumors
by: Hideharu Miura, PhD, et al.
Published: (2023-11-01)

Complete resection and arterial reconstruction for primary sarcoma arising from superior mesenteric artery
by: Shota Hasegawa, MD, et al.
Published: (2022-03-01)

Using Scorecards to Tune Ethos Directive Templates: An Adaptive Radiation Therapy Individualized Approach-Cervix Dosimetric Planning Study
by: Kareem Rayn, MD, et al.
Published: (2024-08-01)

Reoperation of Pulmonary Artery Intimal Sarcoma for Recurrence After Pulmonary Artery Replacement
by: Kentaro Miyazaki, MD, et al.
Published: (2024-09-01)

Dosimetric analysis of varying cord planning organ at risk volume in spine stereotactic body radiation therapy
by: Dawn Owen, MD, PhD, et al.
Published: (2016-01-01)

Management of device-related malignant sarcoma
by: Arash Khamooshian, MD, et al.
Published: (2017-08-01)

Hazards of sparing the ipsilateral parotid gland in the node-positive neck with intensity modulated radiation therapy: Spatial analysis of regional recurrence risk
by: Allen M. Chen, MD, et al.
Published: (2018-04-01)

En bloc resection of visceral aorta and right kidney due to aortic sarcoma using temporary extracorporeal bypass grafting
by: Patrick Björkman, MD, PhD, et al.
Published: (2019-12-01)

A case of pelvic EWSR1-PATZ1 fusion sarcoma treated with carbon ion radiotherapy
by: Toshinari Yagi, MD, et al.
Published: (2024-07-01)

Development and Clinical Implementation of an Automated Virtual Integrative Planner for Radiation Therapy of Head and Neck Cancer
by: Elizabeth M. Jaworski, MD, MS, et al.
Published: (2023-03-01)

Ovarian Transposition Before Pelvic Radiation Therapy: Spatial Distribution and Dose Volume Analysis
by: Christopher Gay, MD, et al.
Published: (2022-01-01)

Long-Term Results of High-Dose 2-Fraction Carbon Ion Radiation Therapy for Hepatocellular Carcinoma
by: Shigeo Yasuda, MD, PhD, et al.
Published: (2020-03-01)

Single-fraction Stereotactic Body Radiation Therapy versus Conventionally Fractionated Radiation Therapy for the Treatment of Prostate Cancer Bone Metastases
by: Robert W. Gao, BS, et al.
Published: (2019-04-01)

Neoadjuvant Chemoradiation Compared With Neoadjuvant Radiation Alone in the Management of High-Grade Soft Tissue Extremity Sarcomas
by: Sarah Z. Hazell, MD, et al.
Published: (2020-03-01)

Comparison Between Dose-Escalated Intensity Modulated Radiation Therapy and 3-Dimensional Conformal Radiation Therapy for Salvage Radiation Therapy After Prostatectomy
by: Nana Shimoyachi, MD, et al.
Published: (2021-11-01)

Ablative Five-Fraction Stereotactic Body Radiation Therapy for Inoperable Pancreatic Cancer Using Online MR-Guided Adaptation
by: Comron Hassanzadeh, MD, MPH, et al.
Published: (2021-01-01)