Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation
Hydroalcoholic gels or hand sanitisers have become essential products to prevent and mitigate the transmission of COVID-19. Depending on their use, they can be classified as cosmetics (cleaning the skin) or biocides (with antimicrobial effects). The aim of this work was to determine sixty personal c...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Methods and Protocols |
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| Online Access: | https://www.mdpi.com/2409-9279/6/5/95 |
| _version_ | 1797572739547004928 |
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| author | Ana Castiñeira-Landeira Lua Vazquez Thierry Dagnac Maria Celeiro María Llompart |
| author_facet | Ana Castiñeira-Landeira Lua Vazquez Thierry Dagnac Maria Celeiro María Llompart |
| author_sort | Ana Castiñeira-Landeira |
| collection | DOAJ |
| description | Hydroalcoholic gels or hand sanitisers have become essential products to prevent and mitigate the transmission of COVID-19. Depending on their use, they can be classified as cosmetics (cleaning the skin) or biocides (with antimicrobial effects). The aim of this work was to determine sixty personal care products frequently found in cosmetic formulations, including fragrance allergens, synthetic musks, preservatives and plasticisers, in hydroalcoholic gels and evaluate their compliance with the current regulation. A simple and fast analytical methodology based on solid-phase microextraction followed by gas chromatography–tandem mass spectrometry (SPME-GC-MS/MS) was validated and applied to 67 real samples. Among the 60 target compounds, 47 of them were found in the analysed hand sanitisers, highlighting the high number of fragrance allergens (up to 23) at concentrations of up to 32,458 μg g<sup>−1</sup>. Most of the samples did not comply with the labelling requirements of the EU Regulation No 1223/2009, and some of them even contained compounds banned in cosmetic products such as plasticisers. Method sustainability was also evaluated using the metric tool AGREEPrep, demonstrating its greenness. |
| first_indexed | 2024-03-10T21:01:04Z |
| format | Article |
| id | doaj.art-dbea96742f70462885f0adb3d7f12669 |
| institution | Directory Open Access Journal |
| issn | 2409-9279 |
| language | English |
| last_indexed | 2024-03-10T21:01:04Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Methods and Protocols |
| spelling | doaj.art-dbea96742f70462885f0adb3d7f126692023-11-19T17:35:06ZengMDPI AGMethods and Protocols2409-92792023-10-01659510.3390/mps6050095Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current RegulationAna Castiñeira-Landeira0Lua Vazquez1Thierry Dagnac2Maria Celeiro3María Llompart4CRETUS, Department of Analytical Chemistry, Nutrition and Food Science, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, SpainCRETUS, Department of Analytical Chemistry, Nutrition and Food Science, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, SpainGalician Agency for Food Quality, Agronomic Research Centre (AGACAL-CIAM), Unit of Organic Contaminants, P.O. Box 10, E-15080 A Coruña, SpainCRETUS, Department of Analytical Chemistry, Nutrition and Food Science, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, SpainCRETUS, Department of Analytical Chemistry, Nutrition and Food Science, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, SpainHydroalcoholic gels or hand sanitisers have become essential products to prevent and mitigate the transmission of COVID-19. Depending on their use, they can be classified as cosmetics (cleaning the skin) or biocides (with antimicrobial effects). The aim of this work was to determine sixty personal care products frequently found in cosmetic formulations, including fragrance allergens, synthetic musks, preservatives and plasticisers, in hydroalcoholic gels and evaluate their compliance with the current regulation. A simple and fast analytical methodology based on solid-phase microextraction followed by gas chromatography–tandem mass spectrometry (SPME-GC-MS/MS) was validated and applied to 67 real samples. Among the 60 target compounds, 47 of them were found in the analysed hand sanitisers, highlighting the high number of fragrance allergens (up to 23) at concentrations of up to 32,458 μg g<sup>−1</sup>. Most of the samples did not comply with the labelling requirements of the EU Regulation No 1223/2009, and some of them even contained compounds banned in cosmetic products such as plasticisers. Method sustainability was also evaluated using the metric tool AGREEPrep, demonstrating its greenness.https://www.mdpi.com/2409-9279/6/5/95hydroalcoholic gelspersonal care productssolid phase microextractiongas chromatographytandem mass spectrometry |
| spellingShingle | Ana Castiñeira-Landeira Lua Vazquez Thierry Dagnac Maria Celeiro María Llompart Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation Methods and Protocols hydroalcoholic gels personal care products solid phase microextraction gas chromatography tandem mass spectrometry |
| title | Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation |
| title_full | Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation |
| title_fullStr | Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation |
| title_full_unstemmed | Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation |
| title_short | Allergens and Other Harmful Substances in Hydroalcoholic Gels: Compliance with Current Regulation |
| title_sort | allergens and other harmful substances in hydroalcoholic gels compliance with current regulation |
| topic | hydroalcoholic gels personal care products solid phase microextraction gas chromatography tandem mass spectrometry |
| url | https://www.mdpi.com/2409-9279/6/5/95 |
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