More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy
Abstract Background Some studies investigated epidemiological and clinical features of laboratory-confirmed patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) the virus causing coronavirus disease 2019 (COVID-19), but limited attention has been paid to the follow-up of hospit...
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| Format: | Article |
| Language: | English |
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BMC
2021-01-01
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| Series: | Respiratory Research |
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| Online Access: | https://doi.org/10.1186/s12931-021-01613-2 |
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| author | Giovanna E. Carpagnano Giovanni Migliore Salvatore Grasso Vito Procacci Emanuela Resta Francesco Panza Onofrio Resta |
| author_facet | Giovanna E. Carpagnano Giovanni Migliore Salvatore Grasso Vito Procacci Emanuela Resta Francesco Panza Onofrio Resta |
| author_sort | Giovanna E. Carpagnano |
| collection | DOAJ |
| description | Abstract Background Some studies investigated epidemiological and clinical features of laboratory-confirmed patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) the virus causing coronavirus disease 2019 (COVID-19), but limited attention has been paid to the follow-up of hospitalized patients on the basis of clinical setting and the expertise of clinical management. Methods In the present single-centered, retrospective, observational study, we reported findings from 87 consecutive laboratory-confirmed COVID-19 patients with moderate-to-severe acute respiratory syndrome hospitalized in an intermediate Respiratory Intensive Care Unit (RICU), subdividing the patients in two groups according to the admission date (before and after March 29, 2020). Results With improved skills in the clinical management of COVID-19, we observed a significant lower mortality in the T2 group compared with the T1 group and a significantly difference in terms of mortality among the patients transferred in Intensive Care Unit (ICU) from our intermediate RICU (100% in T1 group vs. 33.3% in T2 group). The average length of stay in intermediate RICU of ICU-transferred patients who survived in T1 and T2 was significantly longer than those who died (who died 3.3 ± 2.8 days vs. who survived 6.4 ± 3.3 days). T Conclusions The present findings suggested that an intermediate level of hospital care may have the potential to modify survival in COVID-19 patients, particularly in the present phase of a more skilled clinical management of the pandemic. |
| first_indexed | 2024-12-17T04:58:40Z |
| format | Article |
| id | doaj.art-dbeac392da4a4b91b9e536eeb60af413 |
| institution | Directory Open Access Journal |
| issn | 1465-993X |
| language | English |
| last_indexed | 2024-12-17T04:58:40Z |
| publishDate | 2021-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-dbeac392da4a4b91b9e536eeb60af4132022-12-21T22:02:38ZengBMCRespiratory Research1465-993X2021-01-012211710.1186/s12931-021-01613-2More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in ItalyGiovanna E. Carpagnano0Giovanni Migliore1Salvatore Grasso2Vito Procacci3Emanuela Resta4Francesco Panza5Onofrio Resta6Department of Basic Medical Science, Institute of Respiratory Disease, Neuroscience, and Sense Organs, University of Bari “Aldo Moro”General Direction, Policlinico HospitalDepartment of Emergency and Organ Transplantation, Section of Anesthesia and Intensive Care, University of Bari “Aldo Moro”Emergency Department, Policlinico HospitalTranslational Medicine and Health System Management, University of FoggiaPopulation Health Unit, Healthy Aging Phenotypes Research Unit, “Salus in Apulia Study”, National Institute of Gastroenterology “Saverio de Bellis”, Research Hospital, Castellana GrotteDepartment of Basic Medical Science, Institute of Respiratory Disease, Neuroscience, and Sense Organs, University of Bari “Aldo Moro”Abstract Background Some studies investigated epidemiological and clinical features of laboratory-confirmed patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) the virus causing coronavirus disease 2019 (COVID-19), but limited attention has been paid to the follow-up of hospitalized patients on the basis of clinical setting and the expertise of clinical management. Methods In the present single-centered, retrospective, observational study, we reported findings from 87 consecutive laboratory-confirmed COVID-19 patients with moderate-to-severe acute respiratory syndrome hospitalized in an intermediate Respiratory Intensive Care Unit (RICU), subdividing the patients in two groups according to the admission date (before and after March 29, 2020). Results With improved skills in the clinical management of COVID-19, we observed a significant lower mortality in the T2 group compared with the T1 group and a significantly difference in terms of mortality among the patients transferred in Intensive Care Unit (ICU) from our intermediate RICU (100% in T1 group vs. 33.3% in T2 group). The average length of stay in intermediate RICU of ICU-transferred patients who survived in T1 and T2 was significantly longer than those who died (who died 3.3 ± 2.8 days vs. who survived 6.4 ± 3.3 days). T Conclusions The present findings suggested that an intermediate level of hospital care may have the potential to modify survival in COVID-19 patients, particularly in the present phase of a more skilled clinical management of the pandemic.https://doi.org/10.1186/s12931-021-01613-2Critical careAssisted ventilationIntermediate RICUSurvivalPandemicItaly |
| spellingShingle | Giovanna E. Carpagnano Giovanni Migliore Salvatore Grasso Vito Procacci Emanuela Resta Francesco Panza Onofrio Resta More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy Respiratory Research Critical care Assisted ventilation Intermediate RICU Survival Pandemic Italy |
| title | More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy |
| title_full | More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy |
| title_fullStr | More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy |
| title_full_unstemmed | More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy |
| title_short | More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy |
| title_sort | more skilled clinical management of covid 19 patients modified mortality in an intermediate respiratory intensive care unit in italy |
| topic | Critical care Assisted ventilation Intermediate RICU Survival Pandemic Italy |
| url | https://doi.org/10.1186/s12931-021-01613-2 |
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