The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy

Prostate cancer is the most prevalent cancer and the second leading cause of oncological mortality in men. Its prognosis is estimated by normograms based on statistical methods. However, it is still a challenge to accurately determine the pathological stage from clinical data. Our aim is to descr...

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Main Authors: Álvaro Martínez-Bordajandi, Ana Patricia Puga-Mendoza, Gonzalo Granero-Heredia, Cayetano Fernández-Sola, Tomás Fernández-Aparicio, Iria Dobarrio-Sanz, José Manuel Hernández-Padilla
Format: Article
Language:English
Published: MRE Press 2023-07-01
Series:Journal of Men's Health
Subjects:
Online Access:https://oss.jomh.org/files/article/20230731-61/pdf/JOMH2022122801.pdf
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author Álvaro Martínez-Bordajandi
Ana Patricia Puga-Mendoza
Gonzalo Granero-Heredia
Cayetano Fernández-Sola
Tomás Fernández-Aparicio
Iria Dobarrio-Sanz
José Manuel Hernández-Padilla
author_facet Álvaro Martínez-Bordajandi
Ana Patricia Puga-Mendoza
Gonzalo Granero-Heredia
Cayetano Fernández-Sola
Tomás Fernández-Aparicio
Iria Dobarrio-Sanz
José Manuel Hernández-Padilla
author_sort Álvaro Martínez-Bordajandi
collection DOAJ
description Prostate cancer is the most prevalent cancer and the second leading cause of oncological mortality in men. Its prognosis is estimated by normograms based on statistical methods. However, it is still a challenge to accurately determine the pathological stage from clinical data. Our aim is to describe and analyze the relationship between sociodemographic, quality-of-life and clinical variables in patients undergoing a radical prostatectomy. A cross-sectional observational study was carried out and included 51 patients undergoing a radical prostatectomy in a general hospital in southeastern Spain. The normality of all variables was studied. A descriptive and association/correlation analysis of the most relevant variables of the study was carried out. In addition, a multivariate analysis was performed to study the intergroup differences between variables with significant correlation. Age was related to a higher occurrence of erectile dysfunction (f = 10.594, p = 0.09) and to a lower percentage of consultations for this reason (x2 = 6.996, p = 0.012). Overweight/obese patients had a more aggressive result on the Gleason score (w = 151.5, p = 0.019). Differences were found between ultrasound and surgical specimen prostate volume (f = 10.324, p = 0.004). There were differences between the Gleason score result obtained from the biopsy and the surgical specimen (f = 23.330, p = 0.00001). Our results suggest that older age could be related to increased erectile dysfunction, that obesity could be related to more aggressive prostate cancer, and that there can be differences in the Gleason score between the biopsy and the final specimen. These findings suggest that the Gleason score results should be interpreted cautiously.
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spelling doaj.art-dbebfbbaf0a540b9b9488516377f88cb2024-02-03T11:29:49ZengMRE PressJournal of Men's Health1875-68592023-07-01197778510.22514/jomh.2023.059S1875-6867(23)00028-3The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomyÁlvaro Martínez-Bordajandi0Ana Patricia Puga-Mendoza1Gonzalo Granero-Heredia2Cayetano Fernández-Sola3Tomás Fernández-Aparicio4Iria Dobarrio-Sanz5José Manuel Hernández-Padilla6Departament of Anaesthesiology and Surgical Intensive Care, Torrecardenas Universitary Hospital, 04009 Almeria, SpainCommunity Health Centre Retamar, Sanitary District of Almeria, 04131 Almeria, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainDepartment of Urology, Hospital General Universitario Morales Meseguer, 30008 Murcia, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainProstate cancer is the most prevalent cancer and the second leading cause of oncological mortality in men. Its prognosis is estimated by normograms based on statistical methods. However, it is still a challenge to accurately determine the pathological stage from clinical data. Our aim is to describe and analyze the relationship between sociodemographic, quality-of-life and clinical variables in patients undergoing a radical prostatectomy. A cross-sectional observational study was carried out and included 51 patients undergoing a radical prostatectomy in a general hospital in southeastern Spain. The normality of all variables was studied. A descriptive and association/correlation analysis of the most relevant variables of the study was carried out. In addition, a multivariate analysis was performed to study the intergroup differences between variables with significant correlation. Age was related to a higher occurrence of erectile dysfunction (f = 10.594, p = 0.09) and to a lower percentage of consultations for this reason (x2 = 6.996, p = 0.012). Overweight/obese patients had a more aggressive result on the Gleason score (w = 151.5, p = 0.019). Differences were found between ultrasound and surgical specimen prostate volume (f = 10.324, p = 0.004). There were differences between the Gleason score result obtained from the biopsy and the surgical specimen (f = 23.330, p = 0.00001). Our results suggest that older age could be related to increased erectile dysfunction, that obesity could be related to more aggressive prostate cancer, and that there can be differences in the Gleason score between the biopsy and the final specimen. These findings suggest that the Gleason score results should be interpreted cautiously.https://oss.jomh.org/files/article/20230731-61/pdf/JOMH2022122801.pdfprostate cancerprostatectomystaginggleason score
spellingShingle Álvaro Martínez-Bordajandi
Ana Patricia Puga-Mendoza
Gonzalo Granero-Heredia
Cayetano Fernández-Sola
Tomás Fernández-Aparicio
Iria Dobarrio-Sanz
José Manuel Hernández-Padilla
The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
Journal of Men's Health
prostate cancer
prostatectomy
staging
gleason score
title The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
title_full The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
title_fullStr The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
title_full_unstemmed The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
title_short The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
title_sort effect of the discrepancy between pre and post operative staging on decision making and quality of life in men undergoing a radical prostatectomy
topic prostate cancer
prostatectomy
staging
gleason score
url https://oss.jomh.org/files/article/20230731-61/pdf/JOMH2022122801.pdf
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