The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy
Prostate cancer is the most prevalent cancer and the second leading cause of oncological mortality in men. Its prognosis is estimated by normograms based on statistical methods. However, it is still a challenge to accurately determine the pathological stage from clinical data. Our aim is to descr...
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Format: | Article |
Language: | English |
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MRE Press
2023-07-01
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Series: | Journal of Men's Health |
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Online Access: | https://oss.jomh.org/files/article/20230731-61/pdf/JOMH2022122801.pdf |
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author | Álvaro Martínez-Bordajandi Ana Patricia Puga-Mendoza Gonzalo Granero-Heredia Cayetano Fernández-Sola Tomás Fernández-Aparicio Iria Dobarrio-Sanz José Manuel Hernández-Padilla |
author_facet | Álvaro Martínez-Bordajandi Ana Patricia Puga-Mendoza Gonzalo Granero-Heredia Cayetano Fernández-Sola Tomás Fernández-Aparicio Iria Dobarrio-Sanz José Manuel Hernández-Padilla |
author_sort | Álvaro Martínez-Bordajandi |
collection | DOAJ |
description | Prostate cancer is the most prevalent cancer and the second leading cause of
oncological mortality in men. Its prognosis is estimated by normograms based on
statistical methods. However, it is still a challenge to accurately determine the
pathological stage from clinical data. Our aim is to describe and analyze the
relationship between sociodemographic, quality-of-life and clinical variables in
patients undergoing a radical prostatectomy. A cross-sectional observational
study was carried out and included 51 patients undergoing a radical prostatectomy
in a general hospital in southeastern Spain. The normality of all variables was
studied. A descriptive and association/correlation analysis of the most relevant
variables of the study was carried out. In addition, a multivariate analysis was
performed to study the intergroup differences between variables with significant
correlation. Age was related to a higher occurrence of erectile dysfunction (f =
10.594, p = 0.09) and to a lower percentage of consultations for this
reason (x2 = 6.996, p = 0.012). Overweight/obese patients had a
more aggressive result on the Gleason score (w = 151.5, p = 0.019).
Differences were found between ultrasound and surgical specimen prostate volume
(f = 10.324, p = 0.004). There were differences between the Gleason
score result obtained from the biopsy and the surgical specimen (f = 23.330,
p = 0.00001). Our results suggest that older age could be related to
increased erectile dysfunction, that obesity could be related to more aggressive
prostate cancer, and that there can be differences in the Gleason score between
the biopsy and the final specimen. These findings suggest that the Gleason score
results should be interpreted cautiously. |
first_indexed | 2024-03-08T06:31:45Z |
format | Article |
id | doaj.art-dbebfbbaf0a540b9b9488516377f88cb |
institution | Directory Open Access Journal |
issn | 1875-6859 |
language | English |
last_indexed | 2024-03-08T06:31:45Z |
publishDate | 2023-07-01 |
publisher | MRE Press |
record_format | Article |
series | Journal of Men's Health |
spelling | doaj.art-dbebfbbaf0a540b9b9488516377f88cb2024-02-03T11:29:49ZengMRE PressJournal of Men's Health1875-68592023-07-01197778510.22514/jomh.2023.059S1875-6867(23)00028-3The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomyÁlvaro Martínez-Bordajandi0Ana Patricia Puga-Mendoza1Gonzalo Granero-Heredia2Cayetano Fernández-Sola3Tomás Fernández-Aparicio4Iria Dobarrio-Sanz5José Manuel Hernández-Padilla6Departament of Anaesthesiology and Surgical Intensive Care, Torrecardenas Universitary Hospital, 04009 Almeria, SpainCommunity Health Centre Retamar, Sanitary District of Almeria, 04131 Almeria, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainDepartment of Urology, Hospital General Universitario Morales Meseguer, 30008 Murcia, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainDepartment of Nursing, Physiotherapy and Medicine, University of Almeria, 04120 Almeria, SpainProstate cancer is the most prevalent cancer and the second leading cause of oncological mortality in men. Its prognosis is estimated by normograms based on statistical methods. However, it is still a challenge to accurately determine the pathological stage from clinical data. Our aim is to describe and analyze the relationship between sociodemographic, quality-of-life and clinical variables in patients undergoing a radical prostatectomy. A cross-sectional observational study was carried out and included 51 patients undergoing a radical prostatectomy in a general hospital in southeastern Spain. The normality of all variables was studied. A descriptive and association/correlation analysis of the most relevant variables of the study was carried out. In addition, a multivariate analysis was performed to study the intergroup differences between variables with significant correlation. Age was related to a higher occurrence of erectile dysfunction (f = 10.594, p = 0.09) and to a lower percentage of consultations for this reason (x2 = 6.996, p = 0.012). Overweight/obese patients had a more aggressive result on the Gleason score (w = 151.5, p = 0.019). Differences were found between ultrasound and surgical specimen prostate volume (f = 10.324, p = 0.004). There were differences between the Gleason score result obtained from the biopsy and the surgical specimen (f = 23.330, p = 0.00001). Our results suggest that older age could be related to increased erectile dysfunction, that obesity could be related to more aggressive prostate cancer, and that there can be differences in the Gleason score between the biopsy and the final specimen. These findings suggest that the Gleason score results should be interpreted cautiously.https://oss.jomh.org/files/article/20230731-61/pdf/JOMH2022122801.pdfprostate cancerprostatectomystaginggleason score |
spellingShingle | Álvaro Martínez-Bordajandi Ana Patricia Puga-Mendoza Gonzalo Granero-Heredia Cayetano Fernández-Sola Tomás Fernández-Aparicio Iria Dobarrio-Sanz José Manuel Hernández-Padilla The effect of the discrepancy between pre- and post-operative staging on decision-making and quality of life in men undergoing a radical prostatectomy Journal of Men's Health prostate cancer prostatectomy staging gleason score |
title | The effect of the discrepancy between pre- and
post-operative staging on decision-making and quality
of life in men undergoing a radical prostatectomy |
title_full | The effect of the discrepancy between pre- and
post-operative staging on decision-making and quality
of life in men undergoing a radical prostatectomy |
title_fullStr | The effect of the discrepancy between pre- and
post-operative staging on decision-making and quality
of life in men undergoing a radical prostatectomy |
title_full_unstemmed | The effect of the discrepancy between pre- and
post-operative staging on decision-making and quality
of life in men undergoing a radical prostatectomy |
title_short | The effect of the discrepancy between pre- and
post-operative staging on decision-making and quality
of life in men undergoing a radical prostatectomy |
title_sort | effect of the discrepancy between pre and post operative staging on decision making and quality of life in men undergoing a radical prostatectomy |
topic | prostate cancer prostatectomy staging gleason score |
url | https://oss.jomh.org/files/article/20230731-61/pdf/JOMH2022122801.pdf |
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