Klotho sensitizes human lung cancer cell line to cisplatin via PI3k/Akt pathway.

Klotho sensitizes human lung cancer cell line to cisplatin via PI3k/Akt pathway.

Klotho was first identified in 1997 and has been considered as an anti-aging gene. Emerging evidence demonstrates that klotho has a close relationship with cancers, including lung cancer, breast cancer, etc, by inhibiting the proliferation and promoting apoptosis of cancer cells. Cisplatin has been...

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Bibliographic Details
Main Authors: Yan Wang, Lei Chen, Guochang Huang, Dongmei He, Juan He, Wei Xu, Chunying Zou, Feng Zong, Yan Li, Bo Chen, Shuanshuan Wu, Weihong Zhao, Jianqing Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3578855?pdf=render

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