Anti-Osteogenic Effect of Danshensu in Ankylosing Spondylitis: An in Vitro Study Based on Integrated Network Pharmacology

Anti-Osteogenic Effect of Danshensu in Ankylosing Spondylitis: An in Vitro Study Based on Integrated Network Pharmacology

Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by abnormal bone metabolism, with few effective treatments available. Danshensu [3-(3,4-dihydroxy-phenyl) lactic acid) is a bioactive compound from traditional Chinese medicine with a variety of pharmacologic effects. In the...

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Bibliographic Details
Main Authors: Jiaxiao Li, Zexin Chen, Hongbo Liao, Yanting Zhong, Junying Hua, Miaoling Su, Jiahao Li, Jinrong Xu, Liao Cui, Yang Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
ankylosing spondylitis
Danshensu
network pharmacology
ossification
fibroblast
osteoblast
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.772190/full

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