Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series
Abstract Background The brain metastasis from differentiated thyroid carcinoma (DTC) is a rare condition and its prognosis is poor. The standard protocol for screening and treatment of patients with brain metastases from papillary thyroid cancer (PTC) remains controversial. This report aims to share...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | Thyroid Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13044-023-00146-8 |
| _version_ | 1797952655712059392 |
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| author | Le Ngoc Ha Le Quoc Khanh Ngo Thi Minh Hanh Hyo Jung Seo Mai Hong Son |
| author_facet | Le Ngoc Ha Le Quoc Khanh Ngo Thi Minh Hanh Hyo Jung Seo Mai Hong Son |
| author_sort | Le Ngoc Ha |
| collection | DOAJ |
| description | Abstract Background The brain metastasis from differentiated thyroid carcinoma (DTC) is a rare condition and its prognosis is poor. The standard protocol for screening and treatment of patients with brain metastases from papillary thyroid cancer (PTC) remains controversial. This report aims to share the experience of a single center in the management of brain metastases from DTC. Material and methods Five patients with brain metastases were identified from 5000 patients with DTC attending the department of nuclear medicine, Hospital 108 between 2016 to 2022. The statistical software Statistical Package for Social Sciences (SPSS) 20.0 (SPSS Inc., Chicago, IL, USA) was used to analyze the data. Results Five patients with brain metastases from DTC were revealed by MRI, 18F-FDG PET/CT with contrast enhancement, and 131I-SPECT/CT. The median time of overall survival (OS) was 15 months, ranging from 10 to 65 months. Two out of the five patients underwent surgery, and futher 2 patients were treated with stereotactic surgery (SRS). All patients are still alive. Conclusions Brain metastases from DTC are rare. MRI is the preferred imaging mobility to screen brain lesions in DTC. The primary treatment modalities are surgery and SRS. |
| first_indexed | 2024-04-10T22:49:52Z |
| format | Article |
| id | doaj.art-dbee4e7bf3454d09abb0bca48d47fa7e |
| institution | Directory Open Access Journal |
| issn | 1756-6614 |
| language | English |
| last_indexed | 2024-04-10T22:49:52Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Thyroid Research |
| spelling | doaj.art-dbee4e7bf3454d09abb0bca48d47fa7e2023-01-15T12:06:00ZengBMCThyroid Research1756-66142023-01-0116111010.1186/s13044-023-00146-8Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case seriesLe Ngoc Ha0Le Quoc Khanh1Ngo Thi Minh Hanh2Hyo Jung Seo3Mai Hong Son4Department of Nuclear MedicineDepartment of Nuclear MedicineDepartment of Pathology, Hospital 108BNCT CenterDepartment of Nuclear MedicineAbstract Background The brain metastasis from differentiated thyroid carcinoma (DTC) is a rare condition and its prognosis is poor. The standard protocol for screening and treatment of patients with brain metastases from papillary thyroid cancer (PTC) remains controversial. This report aims to share the experience of a single center in the management of brain metastases from DTC. Material and methods Five patients with brain metastases were identified from 5000 patients with DTC attending the department of nuclear medicine, Hospital 108 between 2016 to 2022. The statistical software Statistical Package for Social Sciences (SPSS) 20.0 (SPSS Inc., Chicago, IL, USA) was used to analyze the data. Results Five patients with brain metastases from DTC were revealed by MRI, 18F-FDG PET/CT with contrast enhancement, and 131I-SPECT/CT. The median time of overall survival (OS) was 15 months, ranging from 10 to 65 months. Two out of the five patients underwent surgery, and futher 2 patients were treated with stereotactic surgery (SRS). All patients are still alive. Conclusions Brain metastases from DTC are rare. MRI is the preferred imaging mobility to screen brain lesions in DTC. The primary treatment modalities are surgery and SRS.https://doi.org/10.1186/s13044-023-00146-8Papillary thyroid carcinomaBrain metastasisI- Whole Body Scan18F-FDG PET/CTMRI |
| spellingShingle | Le Ngoc Ha Le Quoc Khanh Ngo Thi Minh Hanh Hyo Jung Seo Mai Hong Son Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series Thyroid Research Papillary thyroid carcinoma Brain metastasis I- Whole Body Scan 18F-FDG PET/CT MRI |
| title | Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series |
| title_full | Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series |
| title_fullStr | Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series |
| title_full_unstemmed | Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series |
| title_short | Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series |
| title_sort | screening and treatment of brain metastasis from papillary thyroid carcinoma a case series |
| topic | Papillary thyroid carcinoma Brain metastasis I- Whole Body Scan 18F-FDG PET/CT MRI |
| url | https://doi.org/10.1186/s13044-023-00146-8 |
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