Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database

Background: Developmental dysplasia of the hip (DDH) is a cluster of hip development disorders that affects infants. The incidence of DDH-related dislocation (DDH-dislocation) is reportedly 0.1–0.3%; however, the nationwide incidence of DDH-dislocation in Japan has not been previously reported. The...

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Main Authors: Hiroki Den, Junichi Ito, Akatsuki Kokaze
Format: Article
Language:English
Published: Japan Epidemiological Association 2023-04-01
Series:Journal of Epidemiology
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jea/33/4/33_JE20210074/_pdf
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author Hiroki Den
Junichi Ito
Akatsuki Kokaze
author_facet Hiroki Den
Junichi Ito
Akatsuki Kokaze
author_sort Hiroki Den
collection DOAJ
description Background: Developmental dysplasia of the hip (DDH) is a cluster of hip development disorders that affects infants. The incidence of DDH-related dislocation (DDH-dislocation) is reportedly 0.1–0.3%; however, the nationwide incidence of DDH-dislocation in Japan has not been previously reported. The primary aim of this study was to report the nationwide incidence of DDH-dislocation in Japan using the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), and to examine its regional variation across Japan. Methods: This was a retrospective birth cohort study using the NDB. Data on patients born between 2011 and 2013 and assigned DDH-dislocation-related disease codes during 2011–2018 were extracted. Among these, patients who underwent treatment for DDH-dislocation between 2011 and 2018 were defined as patients with DDH-dislocation. Results: Across the 2011, 2012, and 2013 birth cohorts, 2,367 patients were diagnosed with DDH-dislocation, yielding the nationwide incidence of 0.076%. Region-specific incidence rates were almost similar across Japan. Secondary analyses revealed that 273 (11.5%) patients were diagnosed at the age of ≥1 year. The effect of birth during the cold months on the incidence of DDH-dislocation was significant (relative risk [RR] = 1.89, 95% confidence interval [CI]: 1.75–2.06). The risk of DDH-dislocation among girls was approximately seven times higher than that among boys. Conclusion: This is the first study to report the nationwide incidence of DDH-dislocation in Japan, which was estimated at 0.076%. The regional variation was trivial and unlikely to be clinically significant. Thus, the incidence rates were approximately equal across all regions in Japan.
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spelling doaj.art-dbef909c20f347078b3de3bf77997b2d2023-04-05T08:23:14ZengJapan Epidemiological AssociationJournal of Epidemiology0917-50401349-90922023-04-0133418619210.2188/jea.JE20210074Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National DatabaseHiroki Den0Junichi Ito1Akatsuki Kokaze2Department of Hygiene, Public Health, and Preventative Medicine, Showa University School of Medicine, Tokyo, JapanDepartment of Orthopaedic Surgery, National Rehabilitation Center for Children with Disabilities, Tokyo, JapanDepartment of Hygiene, Public Health, and Preventative Medicine, Showa University School of Medicine, Tokyo, JapanBackground: Developmental dysplasia of the hip (DDH) is a cluster of hip development disorders that affects infants. The incidence of DDH-related dislocation (DDH-dislocation) is reportedly 0.1–0.3%; however, the nationwide incidence of DDH-dislocation in Japan has not been previously reported. The primary aim of this study was to report the nationwide incidence of DDH-dislocation in Japan using the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), and to examine its regional variation across Japan. Methods: This was a retrospective birth cohort study using the NDB. Data on patients born between 2011 and 2013 and assigned DDH-dislocation-related disease codes during 2011–2018 were extracted. Among these, patients who underwent treatment for DDH-dislocation between 2011 and 2018 were defined as patients with DDH-dislocation. Results: Across the 2011, 2012, and 2013 birth cohorts, 2,367 patients were diagnosed with DDH-dislocation, yielding the nationwide incidence of 0.076%. Region-specific incidence rates were almost similar across Japan. Secondary analyses revealed that 273 (11.5%) patients were diagnosed at the age of ≥1 year. The effect of birth during the cold months on the incidence of DDH-dislocation was significant (relative risk [RR] = 1.89, 95% confidence interval [CI]: 1.75–2.06). The risk of DDH-dislocation among girls was approximately seven times higher than that among boys. Conclusion: This is the first study to report the nationwide incidence of DDH-dislocation in Japan, which was estimated at 0.076%. The regional variation was trivial and unlikely to be clinically significant. Thus, the incidence rates were approximately equal across all regions in Japan.https://www.jstage.jst.go.jp/article/jea/33/4/33_JE20210074/_pdfdevelopmental dysplasia of the hipddhepidemiologynational databaseincidence rate
spellingShingle Hiroki Den
Junichi Ito
Akatsuki Kokaze
Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database
Journal of Epidemiology
developmental dysplasia of the hip
ddh
epidemiology
national database
incidence rate
title Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database
title_full Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database
title_fullStr Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database
title_full_unstemmed Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database
title_short Epidemiology of Developmental Dysplasia of the Hip: Analysis of Japanese National Database
title_sort epidemiology of developmental dysplasia of the hip analysis of japanese national database
topic developmental dysplasia of the hip
ddh
epidemiology
national database
incidence rate
url https://www.jstage.jst.go.jp/article/jea/33/4/33_JE20210074/_pdf
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