Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes

Brain butyrylcholinesterase (BChE) is an attractive target for drugs designed for the treatment of Alzheimer’s disease (AD) in its advanced stages. It also potentially represents a biomarker for progression of this disease. Based on the crystal structure of previously described highly potent, revers...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Stane Pajk, Damijan Knez, Urban Košak, Maja Zorović, Xavier Brazzolotto, Nicolas Coquelle, Florian Nachon, Jacques-Philippe Colletier, Marko Živin, Jure Stojan, Stanislav Gobec
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Taylor & Francis Group 2020-01-01
Saila:Journal of Enzyme Inhibition and Medicinal Chemistry
Gaiak:
Sarrera elektronikoa:http://dx.doi.org/10.1080/14756366.2019.1710502