Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to <italic toggle="yes">Streptococcus pneumoniae</italic> Capsular Polysaccharides

Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to <italic toggle="yes">Streptococcus pneumoniae</italic> Capsular Polysaccharides

ABSTRACT A Luminex-based direct immunoassay (dLIA) platform has been developed to replace the standardized pneumococcal enzyme-linked immunosorbent assay platform. The multiplex dLIA simultaneously measures the concentration of serum immunoglobulin G (IgG) antibodies specific for pneumococcal capsul...

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Bibliographic Details
Main Authors: Danka Pavliakova, Peter C. Giardina, Soraya Moghazeh, Shite Sebastian, Maya Koster, Viliam Pavliak, Andrew McKeen, Roger French, Kathrin U. Jansen, Michael Pride
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSphere
Subjects:
Luminex
development
multiplex
pneumococcal
validation
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00128-18

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