Emerging frontiers in nanomedicine targeted therapy for prostate cancer
Prostate cancer is a prevalent cancer in men, often treated with chemotherapy. However, it tumor cells are clinically grows slowly and is heterogeneous, leading to treatment resistance and recurrence. Nanomedicines, through targeted delivery using nanocarriers, can enhance drug accumulation at the t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Cancer Treatment and Research Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468294223001004 |
| _version_ | 1797387830708666368 |
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| author | Tayo Alex Adekiya Oluwanifemi Owoseni |
| author_facet | Tayo Alex Adekiya Oluwanifemi Owoseni |
| author_sort | Tayo Alex Adekiya |
| collection | DOAJ |
| description | Prostate cancer is a prevalent cancer in men, often treated with chemotherapy. However, it tumor cells are clinically grows slowly and is heterogeneous, leading to treatment resistance and recurrence. Nanomedicines, through targeted delivery using nanocarriers, can enhance drug accumulation at the tumor site, sustain drug release, and counteract drug resistance. In addition, combination therapy using nanomedicines can target multiple cancer pathways, improving effectiveness and addressing tumor heterogeneity. The application of nanomedicine in prostate cancer treatment would be an important strategy in controlling tumor dynamic process as well as improve survival. Thus, this review highlights therapeutic nanoparticles as a solution for prostate cancer chemotherapy, exploring targeting strategies and approaches to combat drug resistance. |
| first_indexed | 2024-03-08T22:31:47Z |
| format | Article |
| id | doaj.art-dbf4a410efe24c6c915bad50b15cc166 |
| institution | Directory Open Access Journal |
| issn | 2468-2942 |
| language | English |
| last_indexed | 2024-03-08T22:31:47Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cancer Treatment and Research Communications |
| spelling | doaj.art-dbf4a410efe24c6c915bad50b15cc1662023-12-18T04:24:45ZengElsevierCancer Treatment and Research Communications2468-29422023-01-0137100778Emerging frontiers in nanomedicine targeted therapy for prostate cancerTayo Alex Adekiya0Oluwanifemi Owoseni1Corresponding author.; Department of Pharmaceutical Sciences, Howard University, Washington, DC 20059, United StatesDepartment of Pharmaceutical Sciences, Howard University, Washington, DC 20059, United StatesProstate cancer is a prevalent cancer in men, often treated with chemotherapy. However, it tumor cells are clinically grows slowly and is heterogeneous, leading to treatment resistance and recurrence. Nanomedicines, through targeted delivery using nanocarriers, can enhance drug accumulation at the tumor site, sustain drug release, and counteract drug resistance. In addition, combination therapy using nanomedicines can target multiple cancer pathways, improving effectiveness and addressing tumor heterogeneity. The application of nanomedicine in prostate cancer treatment would be an important strategy in controlling tumor dynamic process as well as improve survival. Thus, this review highlights therapeutic nanoparticles as a solution for prostate cancer chemotherapy, exploring targeting strategies and approaches to combat drug resistance.http://www.sciencedirect.com/science/article/pii/S2468294223001004Prostate cancerNanomedicineNanoparticlesChemotherapyResistanceTargeted drug delivery systems |
| spellingShingle | Tayo Alex Adekiya Oluwanifemi Owoseni Emerging frontiers in nanomedicine targeted therapy for prostate cancer Cancer Treatment and Research Communications Prostate cancer Nanomedicine Nanoparticles Chemotherapy Resistance Targeted drug delivery systems |
| title | Emerging frontiers in nanomedicine targeted therapy for prostate cancer |
| title_full | Emerging frontiers in nanomedicine targeted therapy for prostate cancer |
| title_fullStr | Emerging frontiers in nanomedicine targeted therapy for prostate cancer |
| title_full_unstemmed | Emerging frontiers in nanomedicine targeted therapy for prostate cancer |
| title_short | Emerging frontiers in nanomedicine targeted therapy for prostate cancer |
| title_sort | emerging frontiers in nanomedicine targeted therapy for prostate cancer |
| topic | Prostate cancer Nanomedicine Nanoparticles Chemotherapy Resistance Targeted drug delivery systems |
| url | http://www.sciencedirect.com/science/article/pii/S2468294223001004 |
| work_keys_str_mv | AT tayoalexadekiya emergingfrontiersinnanomedicinetargetedtherapyforprostatecancer AT oluwanifemiowoseni emergingfrontiersinnanomedicinetargetedtherapyforprostatecancer |