Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma

Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma

Abstract The crosstalk between cuproptosis and the tumor immune microenvironment (TIME) is vital during clear cell renal cell carcinoma (ccRCC) malignant progression. However, the underlying molecular mechanisms regulate this cross-talk remain elusive. Through tailored machine learning, we analyze c...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhifei Che, Wenyi Jin, Yaoxi Wu, Haoyong Li, Peiyu Liang
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2024-11-01
Serie:Scientific Reports
Ämnen:
Rhomboid-like 2
Cuproptosis
Wnt/β-catenin
Regulatory T cells
Clear cell renal cell carcinoma
Länkar:https://doi.org/10.1038/s41598-024-78713-8

Internet

https://doi.org/10.1038/s41598-024-78713-8

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