LOCAS--a low coverage assembly tool for resequencing projects.

MOTIVATION: Next Generation Sequencing (NGS) is a frequently applied approach to detect sequence variations between highly related genomes. Recent large-scale re-sequencing studies as the Human 1000 Genomes Project utilize NGS data of low coverage to afford sequencing of hundreds of individuals. Her...

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Bibliographic Details
Main Authors: Juliane D Klein, Stephan Ossowski, Korbinian Schneeberger, Detlef Weigel, Daniel H Huson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3156226?pdf=render