Cancer-associated fibroblast-related gene signatures predict survival and drug response in patients with colorectal cancer

Cancer-associated fibroblast-related gene signatures predict survival and drug response in patients with colorectal cancer

Background: Cancer-associated fibroblasts (CAFs) play an important role in the tumorigenesis, immunosuppression and metastasis of colorectal cancer (CRC), and can predict poor prognosis in patients with CRC. The present study aimed to construct a CAFs-related prognostic signature for CRC.Methods: Th...

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Bibliographic Details
Main Authors:	Lei Zhang, Chao Xu, Si-Han Wang, Qin-Wen Ge, Xiao-Wei Wang, Pan Xiao, Qing-Hua Yao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Genetics
Subjects:	colorectal cancer cancer-associated fibroblasts tumor microenvironment prognosis WGCNA
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2022.1054152/full

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