Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG

An increasing number of dog bite victims were being presented to public hospitals in Himachal Pradesh in 2014 amidst virtual non availability of any rabies immunoglobulin (RIG). Only a small quantity of equine rabies immunoglobulin (eRIG) was available from the government owned Central Research Inst...

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Main Authors: Omesh Kumar Bharti, Shampur Narayan Madhusudana, Henry Wilde
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2016.1255834
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author Omesh Kumar Bharti
Shampur Narayan Madhusudana
Henry Wilde
author_facet Omesh Kumar Bharti
Shampur Narayan Madhusudana
Henry Wilde
author_sort Omesh Kumar Bharti
collection DOAJ
description An increasing number of dog bite victims were being presented to public hospitals in Himachal Pradesh in 2014 amidst virtual non availability of any rabies immunoglobulin (RIG). Only a small quantity of equine rabies immunoglobulin (eRIG) was available from the government owned Central Research Institute (CRI) Kasauli. This available eRIG was used in 269 patients as an emergency response and only for local infiltration of severe bite wounds by suspected rabid dogs. This was followed by rabies vaccination, using the WHO approved intra-dermal Thai Red Cross Society vaccination schedule. A subgroup of 26 patients were later identified who had been severely bitten by laboratory confirmed rabid dogs. They were followed for more than one year and all were found to be alive.
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spelling doaj.art-dbfe5e1706314ec890bf30f5b556d8c32023-09-25T11:00:55ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2017-04-0113476276510.1080/21645515.2016.12558341255834Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIGOmesh Kumar Bharti0Shampur Narayan Madhusudana1Henry Wilde2State Intra-dermal Anti-rabies Clinic and Research Centre, DDU Zonal Hospital Shimla, Government of Himachal PradeshWHO-Collaborating Centre for Reference and Research on Rabies, NIMHANSFaculty of Medicine and King Chulalongkorn Memorial Hospital, Chulalongkorn UniversityAn increasing number of dog bite victims were being presented to public hospitals in Himachal Pradesh in 2014 amidst virtual non availability of any rabies immunoglobulin (RIG). Only a small quantity of equine rabies immunoglobulin (eRIG) was available from the government owned Central Research Institute (CRI) Kasauli. This available eRIG was used in 269 patients as an emergency response and only for local infiltration of severe bite wounds by suspected rabid dogs. This was followed by rabies vaccination, using the WHO approved intra-dermal Thai Red Cross Society vaccination schedule. A subgroup of 26 patients were later identified who had been severely bitten by laboratory confirmed rabid dogs. They were followed for more than one year and all were found to be alive.http://dx.doi.org/10.1080/21645515.2016.1255834animal bitespost-exposure prophylaxisrabiesrabies immunoglobulinwound injection
spellingShingle Omesh Kumar Bharti
Shampur Narayan Madhusudana
Henry Wilde
Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG
Human Vaccines & Immunotherapeutics
animal bites
post-exposure prophylaxis
rabies
rabies immunoglobulin
wound injection
title Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG
title_full Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG
title_fullStr Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG
title_full_unstemmed Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG
title_short Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG
title_sort injecting rabies immunoglobulin rig into wounds only a significant saving of lives and costly rig
topic animal bites
post-exposure prophylaxis
rabies
rabies immunoglobulin
wound injection
url http://dx.doi.org/10.1080/21645515.2016.1255834
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AT henrywilde injectingrabiesimmunoglobulinrigintowoundsonlyasignificantsavingoflivesandcostlyrig