A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering
Bone tissue engineering is an interdisciplinary field where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. Among many alternatives, elect...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-08-01
|
| Series: | Membranes |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2077-0375/8/3/62 |
| _version_ | 1827884373751365632 |
|---|---|
| author | Deval Prasad Bhattarai Ludwig Erik Aguilar Chan Hee Park Cheol Sang Kim |
| author_facet | Deval Prasad Bhattarai Ludwig Erik Aguilar Chan Hee Park Cheol Sang Kim |
| author_sort | Deval Prasad Bhattarai |
| collection | DOAJ |
| description | Bone tissue engineering is an interdisciplinary field where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. Among many alternatives, electrospinning is a promising and versatile technique that is used to fabricate polymer fibrous scaffolds for bone tissue engineering applications. Copolymerization and polymer blending is a promising strategic way in purpose of getting synergistic and additive effect achieved from either polymer. In this review, we summarize the basic chemistry of bone, principle of electrospinning, and polymers that are used in bone tissue engineering. Particular attention will be given on biomechanical properties and biological activities of these electrospun fibers. This review will cover the fundamental basis of cell adhesion, differentiation, and proliferation of the electrospun fibers in bone tissue scaffolds. In the last section, we offer the current development and future perspectives on the use of electrospun mats in bone tissue engineering. |
| first_indexed | 2024-03-12T19:28:05Z |
| format | Article |
| id | doaj.art-dc071e35f1194391b6555139a73a10da |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-12T19:28:05Z |
| publishDate | 2018-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-dc071e35f1194391b6555139a73a10da2023-08-02T04:49:10ZengMDPI AGMembranes2077-03752018-08-01836210.3390/membranes8030062membranes8030062A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue EngineeringDeval Prasad Bhattarai0Ludwig Erik Aguilar1Chan Hee Park2Cheol Sang Kim3Department of Bionanosystem Engineering, Graduate School, Chonbuk National University, Jeonju 561-756, KoreaDepartment of Bionanosystem Engineering, Graduate School, Chonbuk National University, Jeonju 561-756, KoreaDepartment of Bionanosystem Engineering, Graduate School, Chonbuk National University, Jeonju 561-756, KoreaDepartment of Bionanosystem Engineering, Graduate School, Chonbuk National University, Jeonju 561-756, KoreaBone tissue engineering is an interdisciplinary field where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. Among many alternatives, electrospinning is a promising and versatile technique that is used to fabricate polymer fibrous scaffolds for bone tissue engineering applications. Copolymerization and polymer blending is a promising strategic way in purpose of getting synergistic and additive effect achieved from either polymer. In this review, we summarize the basic chemistry of bone, principle of electrospinning, and polymers that are used in bone tissue engineering. Particular attention will be given on biomechanical properties and biological activities of these electrospun fibers. This review will cover the fundamental basis of cell adhesion, differentiation, and proliferation of the electrospun fibers in bone tissue scaffolds. In the last section, we offer the current development and future perspectives on the use of electrospun mats in bone tissue engineering.http://www.mdpi.com/2077-0375/8/3/62bone tissue regenerationelectrospinningbiocompatible polymersnanotechnologybiomimicry |
| spellingShingle | Deval Prasad Bhattarai Ludwig Erik Aguilar Chan Hee Park Cheol Sang Kim A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering Membranes bone tissue regeneration electrospinning biocompatible polymers nanotechnology biomimicry |
| title | A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering |
| title_full | A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering |
| title_fullStr | A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering |
| title_full_unstemmed | A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering |
| title_short | A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering |
| title_sort | review on properties of natural and synthetic based electrospun fibrous materials for bone tissue engineering |
| topic | bone tissue regeneration electrospinning biocompatible polymers nanotechnology biomimicry |
| url | http://www.mdpi.com/2077-0375/8/3/62 |
| work_keys_str_mv | AT devalprasadbhattarai areviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT ludwigerikaguilar areviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT chanheepark areviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT cheolsangkim areviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT devalprasadbhattarai reviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT ludwigerikaguilar reviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT chanheepark reviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering AT cheolsangkim reviewonpropertiesofnaturalandsyntheticbasedelectrospunfibrousmaterialsforbonetissueengineering |