Features Immunodiagnostic Local Forms of Tuberculosis in Children
The 100 children with local forms of tuberculosis (LFT) were examinated used by the method of continuous sampling. The results of the LFT immunodiagnostic with the Diaskintest (DST) in the children were evaluated. Diaskintest were started applying in Samara one of the first from Russia. The confirma...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Numikom LLC
2015-08-01
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| Series: | Эпидемиология и вакцинопрофилактика |
| Subjects: | |
| Online Access: | https://www.epidemvac.ru/jour/article/view/376 |
| _version_ | 1797879699670564864 |
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| author | E. A. Borodulina T. E. Ahmerova Zh. P. Vasneva E. S. Eremenkо B. E. Borodulin E. A. Amosova |
| author_facet | E. A. Borodulina T. E. Ahmerova Zh. P. Vasneva E. S. Eremenkо B. E. Borodulin E. A. Amosova |
| author_sort | E. A. Borodulina |
| collection | DOAJ |
| description | The 100 children with local forms of tuberculosis (LFT) were examinated used by the method of continuous sampling. The results of the LFT immunodiagnostic with the Diaskintest (DST) in the children were evaluated. Diaskintest were started applying in Samara one of the first from Russia. The confirmation of the tuberculosis in children with LFT was done in 99% of cases by the positive skin tuberculin tests and in 84% by Diaskintest positive. It is shown that Diaskintest can not be taken as an absolute diagnostic criteria for the diagnosis of the tuberculosis. Were noted that the FGA stimulated IFN-γγ production level were significantly reduced (1,7 times), the DST stimulated IFN-γγ production level were elevated more than 18 pg/ml in the children with negative skin Diaskintest. This observation shows that the issues in the fields of tuberculosis immunodiagnostic require further investigations. |
| first_indexed | 2024-04-10T02:52:33Z |
| format | Article |
| id | doaj.art-dc07a053279748aaa99a0bfe4511fd9d |
| institution | Directory Open Access Journal |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| last_indexed | 2024-04-10T02:52:33Z |
| publishDate | 2015-08-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj.art-dc07a053279748aaa99a0bfe4511fd9d2023-03-13T07:43:12ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942015-08-01144182210.31631/2073-3046-2015-14-4-18-22375Features Immunodiagnostic Local Forms of Tuberculosis in ChildrenE. A. Borodulina0T. E. Ahmerova1Zh. P. Vasneva2E. S. Eremenkо3B. E. Borodulin4E. A. Amosova5Самарский государственный медицинский университетСамарский государственный медицинский университетСамарский диагностический центрСамарский государственный медицинский университетСамарский государственный медицинский университетСамарский государственный медицинский университетThe 100 children with local forms of tuberculosis (LFT) were examinated used by the method of continuous sampling. The results of the LFT immunodiagnostic with the Diaskintest (DST) in the children were evaluated. Diaskintest were started applying in Samara one of the first from Russia. The confirmation of the tuberculosis in children with LFT was done in 99% of cases by the positive skin tuberculin tests and in 84% by Diaskintest positive. It is shown that Diaskintest can not be taken as an absolute diagnostic criteria for the diagnosis of the tuberculosis. Were noted that the FGA stimulated IFN-γγ production level were significantly reduced (1,7 times), the DST stimulated IFN-γγ production level were elevated more than 18 pg/ml in the children with negative skin Diaskintest. This observation shows that the issues in the fields of tuberculosis immunodiagnostic require further investigations.https://www.epidemvac.ru/jour/article/view/376препарат диаскинтест®туберкулезпроба мантумикобактерия туберкулезатуберкулинодиагностикаиммунодиагностикаifn-γ |
| spellingShingle | E. A. Borodulina T. E. Ahmerova Zh. P. Vasneva E. S. Eremenkо B. E. Borodulin E. A. Amosova Features Immunodiagnostic Local Forms of Tuberculosis in Children Эпидемиология и вакцинопрофилактика препарат диаскинтест® туберкулез проба манту микобактерия туберкулеза туберкулинодиагностика иммунодиагностика ifn-γ |
| title | Features Immunodiagnostic Local Forms of Tuberculosis in Children |
| title_full | Features Immunodiagnostic Local Forms of Tuberculosis in Children |
| title_fullStr | Features Immunodiagnostic Local Forms of Tuberculosis in Children |
| title_full_unstemmed | Features Immunodiagnostic Local Forms of Tuberculosis in Children |
| title_short | Features Immunodiagnostic Local Forms of Tuberculosis in Children |
| title_sort | features immunodiagnostic local forms of tuberculosis in children |
| topic | препарат диаскинтест® туберкулез проба манту микобактерия туберкулеза туберкулинодиагностика иммунодиагностика ifn-γ |
| url | https://www.epidemvac.ru/jour/article/view/376 |
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