Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study

Abstract Autism spectrum is a brain development condition that impairs an individual’s capacity to communicate socially and manifests through strict routines and obsessive–compulsive behavior. Applied behavior analysis (ABA) is the gold-standard treatment for autism spectrum disorder (ASD). However,...

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Main Authors: Manu Kohli, Arpan Kumar Kar, Anjali Bangalore, Prathosh AP
Format: Article
Language:English
Published: SpringerOpen 2022-07-01
Series:Brain Informatics
Subjects:
Online Access:https://doi.org/10.1186/s40708-022-00164-6
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author Manu Kohli
Arpan Kumar Kar
Anjali Bangalore
Prathosh AP
author_facet Manu Kohli
Arpan Kumar Kar
Anjali Bangalore
Prathosh AP
author_sort Manu Kohli
collection DOAJ
description Abstract Autism spectrum is a brain development condition that impairs an individual’s capacity to communicate socially and manifests through strict routines and obsessive–compulsive behavior. Applied behavior analysis (ABA) is the gold-standard treatment for autism spectrum disorder (ASD). However, as the number of ASD cases increases, there is a substantial shortage of licensed ABA practitioners, limiting the timely formulation, revision, and implementation of treatment plans and goals. Additionally, the subjectivity of the clinician and a lack of data-driven decision-making affect treatment quality. We address these obstacles by applying two machine learning algorithms to recommend and personalize ABA treatment goals for 29 study participants with ASD. The patient similarity and collaborative filtering methods predicted ABA treatment with an average accuracy of 81–84%, with a normalized discounted cumulative gain of 79–81% (NDCG) compared to clinician-prepared ABA treatment recommendations. Additionally, we assess the two models’ treatment efficacy (TE) by measuring the percentage of recommended treatment goals mastered by the study participants. The proposed treatment recommendation and personalization strategy are generalizable to other intervention methods in addition to ABA and for other brain disorders. This study was registered as a clinical trial on November 5, 2020 with trial registration number CTRI/2020/11/028933.
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spelling doaj.art-dc08cdc3395b4101bc538111b7b6fc522022-12-22T02:05:48ZengSpringerOpenBrain Informatics2198-40182198-40262022-07-019112510.1186/s40708-022-00164-6Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory studyManu Kohli0Arpan Kumar Kar1Anjali Bangalore2Prathosh AP3Indian Institute of Technology-Delhi, Department of Management StudiesIndian Institute of Technology-Delhi, Department of Management StudiesICON CentreIndian Institute of ScienceAbstract Autism spectrum is a brain development condition that impairs an individual’s capacity to communicate socially and manifests through strict routines and obsessive–compulsive behavior. Applied behavior analysis (ABA) is the gold-standard treatment for autism spectrum disorder (ASD). However, as the number of ASD cases increases, there is a substantial shortage of licensed ABA practitioners, limiting the timely formulation, revision, and implementation of treatment plans and goals. Additionally, the subjectivity of the clinician and a lack of data-driven decision-making affect treatment quality. We address these obstacles by applying two machine learning algorithms to recommend and personalize ABA treatment goals for 29 study participants with ASD. The patient similarity and collaborative filtering methods predicted ABA treatment with an average accuracy of 81–84%, with a normalized discounted cumulative gain of 79–81% (NDCG) compared to clinician-prepared ABA treatment recommendations. Additionally, we assess the two models’ treatment efficacy (TE) by measuring the percentage of recommended treatment goals mastered by the study participants. The proposed treatment recommendation and personalization strategy are generalizable to other intervention methods in addition to ABA and for other brain disorders. This study was registered as a clinical trial on November 5, 2020 with trial registration number CTRI/2020/11/028933.https://doi.org/10.1186/s40708-022-00164-6ABAASDAutismCollaborative filteringMachine learningPatient similarity
spellingShingle Manu Kohli
Arpan Kumar Kar
Anjali Bangalore
Prathosh AP
Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study
Brain Informatics
ABA
ASD
Autism
Collaborative filtering
Machine learning
Patient similarity
title Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study
title_full Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study
title_fullStr Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study
title_full_unstemmed Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study
title_short Machine learning-based ABA treatment recommendation and personalization for autism spectrum disorder: an exploratory study
title_sort machine learning based aba treatment recommendation and personalization for autism spectrum disorder an exploratory study
topic ABA
ASD
Autism
Collaborative filtering
Machine learning
Patient similarity
url https://doi.org/10.1186/s40708-022-00164-6
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AT arpankumarkar machinelearningbasedabatreatmentrecommendationandpersonalizationforautismspectrumdisorderanexploratorystudy
AT anjalibangalore machinelearningbasedabatreatmentrecommendationandpersonalizationforautismspectrumdisorderanexploratorystudy
AT prathoshap machinelearningbasedabatreatmentrecommendationandpersonalizationforautismspectrumdisorderanexploratorystudy