A method for validating the accuracy of NMR protein structures
The authors present a method for calculating the accuracy of an NMR structure, where flexibility from backbone chemical shifts is compared to structural flexibility predicted using rigidity theory. The authors validate their method and use it to compare the accuracy of NMR and X-ray structures.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20177-1 |
| _version_ | 1818749496723505152 |
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| author | Nicholas J. Fowler Adnan Sljoka Mike P. Williamson |
| author_facet | Nicholas J. Fowler Adnan Sljoka Mike P. Williamson |
| author_sort | Nicholas J. Fowler |
| collection | DOAJ |
| description | The authors present a method for calculating the accuracy of an NMR structure, where flexibility from backbone chemical shifts is compared to structural flexibility predicted using rigidity theory. The authors validate their method and use it to compare the accuracy of NMR and X-ray structures. |
| first_indexed | 2024-12-18T04:04:42Z |
| format | Article |
| id | doaj.art-dc0ae5ec23644d9c8bc3fe69e0084868 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:04:42Z |
| publishDate | 2020-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-dc0ae5ec23644d9c8bc3fe69e00848682022-12-21T21:21:36ZengNature PortfolioNature Communications2041-17232020-12-0111111110.1038/s41467-020-20177-1A method for validating the accuracy of NMR protein structuresNicholas J. Fowler0Adnan Sljoka1Mike P. Williamson2Dept of Molecular Biology and Biotechnology, University of SheffieldRIKEN Center for Advanced Intelligence Project, RIKENDept of Molecular Biology and Biotechnology, University of SheffieldThe authors present a method for calculating the accuracy of an NMR structure, where flexibility from backbone chemical shifts is compared to structural flexibility predicted using rigidity theory. The authors validate their method and use it to compare the accuracy of NMR and X-ray structures.https://doi.org/10.1038/s41467-020-20177-1 |
| spellingShingle | Nicholas J. Fowler Adnan Sljoka Mike P. Williamson A method for validating the accuracy of NMR protein structures Nature Communications |
| title | A method for validating the accuracy of NMR protein structures |
| title_full | A method for validating the accuracy of NMR protein structures |
| title_fullStr | A method for validating the accuracy of NMR protein structures |
| title_full_unstemmed | A method for validating the accuracy of NMR protein structures |
| title_short | A method for validating the accuracy of NMR protein structures |
| title_sort | method for validating the accuracy of nmr protein structures |
| url | https://doi.org/10.1038/s41467-020-20177-1 |
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