The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial

Background: A significant percent of infertile varicocele patients remained infertile after varicocelectomy and finally most of them refer for assisted reproductive technique (ART) procedures as intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI...

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Main Authors: Ali Asghar Ketabchi, Sohrab Mohammad Salehi, Shirin Salajghah
Format: Article
Language:English
Published: Kerman University of Medical Sciences 2018-11-01
Series:Journal of Kerman University of Medical Sciences
Subjects:
Online Access:https://jkmu.kmu.ac.ir/article_85248_cd3917e1c73fcf50282d4ec4fb33e32a.pdf
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author Ali Asghar Ketabchi
Sohrab Mohammad Salehi
Shirin Salajghah
author_facet Ali Asghar Ketabchi
Sohrab Mohammad Salehi
Shirin Salajghah
author_sort Ali Asghar Ketabchi
collection DOAJ
description Background: A significant percent of infertile varicocele patients remained infertile after varicocelectomy and finally most of them refer for assisted reproductive technique (ART) procedures as intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). In order to achieve the best results, more strict and accurate standards for assessment of sperm parameters, as Kruger standards, are required. Objective:The main goal of this study was to evaluate the efficacy of varicocelectomy onimproving selection of ARTs on the base of Kruger strict morphology test. Method: In a randomized clinical trial study, the results of sperm parameters analysis by Kruger strict morphology test were compared between a group of 67 infertile operated patients and a group of 71 matched no operated men in one-year duration. Results: The selection of better ART levels (IUI vs. ICSI) after varicocelectomy was higher in the operated group than controls (p <0.05). Pregnancy rates (achieving full-term pregnancy by natural cycle intercourse), after one year, were respectively 53.84% and 42.25% in the two groups of operated and non-operated (p=0.082). Conclusion: According to our results, varicocelectomy improves the ART level selection and also may improve pregnancy success rates (both by natural cycle intercourse and ART procedures).
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spelling doaj.art-dc0be299e3b7453d93aafc169f67de7f2023-07-01T05:17:48ZengKerman University of Medical SciencesJournal of Kerman University of Medical Sciences2008-28432018-11-0125651952785248The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical TrialAli Asghar Ketabchi0Sohrab Mohammad Salehi1Shirin Salajghah2Associate Professor of Urology, Physiology Research Center, Kerman Medical Sciences University, Kerman, IranUrology Resident, Kerman Medical Sciences University, Kerman, IranAnesthesia Department, Physiology Research Center, Kerman Medical Sciences University, Kerman, IranBackground: A significant percent of infertile varicocele patients remained infertile after varicocelectomy and finally most of them refer for assisted reproductive technique (ART) procedures as intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). In order to achieve the best results, more strict and accurate standards for assessment of sperm parameters, as Kruger standards, are required. Objective:The main goal of this study was to evaluate the efficacy of varicocelectomy onimproving selection of ARTs on the base of Kruger strict morphology test. Method: In a randomized clinical trial study, the results of sperm parameters analysis by Kruger strict morphology test were compared between a group of 67 infertile operated patients and a group of 71 matched no operated men in one-year duration. Results: The selection of better ART levels (IUI vs. ICSI) after varicocelectomy was higher in the operated group than controls (p <0.05). Pregnancy rates (achieving full-term pregnancy by natural cycle intercourse), after one year, were respectively 53.84% and 42.25% in the two groups of operated and non-operated (p=0.082). Conclusion: According to our results, varicocelectomy improves the ART level selection and also may improve pregnancy success rates (both by natural cycle intercourse and ART procedures).https://jkmu.kmu.ac.ir/article_85248_cd3917e1c73fcf50282d4ec4fb33e32a.pdfvaricocelesemen analysisassisted reproductive techniqueskruger strict morphology test
spellingShingle Ali Asghar Ketabchi
Sohrab Mohammad Salehi
Shirin Salajghah
The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial
Journal of Kerman University of Medical Sciences
varicocele
semen analysis
assisted reproductive techniques
kruger strict morphology test
title The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial
title_full The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial
title_fullStr The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial
title_full_unstemmed The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial
title_short The Effect of Varicocelectomy on Assisted Reproductive Technique Indications and Outcomes based on Kruger Strict Morphology Test: a Randomized Clinical Trial
title_sort effect of varicocelectomy on assisted reproductive technique indications and outcomes based on kruger strict morphology test a randomized clinical trial
topic varicocele
semen analysis
assisted reproductive techniques
kruger strict morphology test
url https://jkmu.kmu.ac.ir/article_85248_cd3917e1c73fcf50282d4ec4fb33e32a.pdf
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