A long-lasting porcine model of ARDS caused by pneumonia and ventilator-induced lung injury

A long-lasting porcine model of ARDS caused by pneumonia and ventilator-induced lung injury

Abstract Background Animal models of acute respiratory distress syndrome (ARDS) do not completely resemble human ARDS, struggling translational research. We aimed to characterize a porcine model of ARDS induced by pneumonia—the most common risk factor in humans—and analyze the additional effect of v...

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Bibliographic Details
Main Authors: Enric Barbeta, Marta Arrieta, Ana Motos, Joaquim Bobi, Hua Yang, Minlan Yang, Giacomo Tanzella, Pierluigi Di Ginnatale, Stefano Nogas, Carmen Rosa Vargas, Roberto Cabrera, Denise Battaglini, Andrea Meli, Kasra Kiarostami, Nil Vázquez, Laia Fernández-Barat, Montserrat Rigol, Ricard Mellado-Artigas, Gerard Frigola, Marta Camprubí-Rimblas, Pau Ferrer, Daniel Martinez, Antonio Artigas, Carlos Ferrando, Miquel Ferrer, Antoni Torres
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Critical Care
Subjects:
ARDS
Ventilator-induced lung injury
Porcine model
Pneumonia
Double hit
Injurious mechanical ventilation
Online Access:https://doi.org/10.1186/s13054-023-04512-8

Internet

https://doi.org/10.1186/s13054-023-04512-8

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