Detection of SARS-COV-2 Proteins Using an ELISA Test
The coronavirus disease 2019 (COVID-19) global pandemic created an unprecedented public health emergency. Early recognition of an infected person and disruption of the transmission pathway are the keys to controlling this major public health threat around the world. The scientifically reliable scree...
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Format: | Article |
Language: | English |
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MDPI AG
2021-04-01
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Series: | Diagnostics |
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Online Access: | https://www.mdpi.com/2075-4418/11/4/698 |
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author | Marina Di Domenico Alfredo De Rosa Mariarosaria Boccellino |
author_facet | Marina Di Domenico Alfredo De Rosa Mariarosaria Boccellino |
author_sort | Marina Di Domenico |
collection | DOAJ |
description | The coronavirus disease 2019 (COVID-19) global pandemic created an unprecedented public health emergency. Early recognition of an infected person and disruption of the transmission pathway are the keys to controlling this major public health threat around the world. The scientifically reliable screening method is an RT-PCR test that is performed on an ororhinopharyngeal swab in the laboratory. In the current severe SARS-CoV-2 pandemic, it is necessary to identify devices for rapid diagnosis to reduce the spread of the disease. The aim of this study was to provide a qualitative, rapid, sensitive, and specific method for a diagnosis of SARS-CoV-2 infection based on the recognition of specific antigens of the SARS-CoV-2 virus. The device was built by assembling commercially available and custom-made semi-finished products. The method was performed in environments outside the laboratory, i.e., “patient side,” with an immediate chemocolorimetric response or with a digital reader using an ELISA method. |
first_indexed | 2024-03-09T04:59:32Z |
format | Article |
id | doaj.art-dc12b93c7c1f4ecca7186df6ba71c9d2 |
institution | Directory Open Access Journal |
issn | 2075-4418 |
language | English |
last_indexed | 2024-03-09T04:59:32Z |
publishDate | 2021-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Diagnostics |
spelling | doaj.art-dc12b93c7c1f4ecca7186df6ba71c9d22023-12-03T13:02:43ZengMDPI AGDiagnostics2075-44182021-04-0111469810.3390/diagnostics11040698Detection of SARS-COV-2 Proteins Using an ELISA TestMarina Di Domenico0Alfredo De Rosa1Mariarosaria Boccellino2Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, 81100 Naples, ItalyMultidisciplinary Medical-Surgical Department, Odontostomatology Section, University of Campania “Luigi Vanvitelli”, 81100 Naples, ItalyDepartment of Precision Medicine, University of Campania “Luigi Vanvitelli”, 81100 Naples, ItalyThe coronavirus disease 2019 (COVID-19) global pandemic created an unprecedented public health emergency. Early recognition of an infected person and disruption of the transmission pathway are the keys to controlling this major public health threat around the world. The scientifically reliable screening method is an RT-PCR test that is performed on an ororhinopharyngeal swab in the laboratory. In the current severe SARS-CoV-2 pandemic, it is necessary to identify devices for rapid diagnosis to reduce the spread of the disease. The aim of this study was to provide a qualitative, rapid, sensitive, and specific method for a diagnosis of SARS-CoV-2 infection based on the recognition of specific antigens of the SARS-CoV-2 virus. The device was built by assembling commercially available and custom-made semi-finished products. The method was performed in environments outside the laboratory, i.e., “patient side,” with an immediate chemocolorimetric response or with a digital reader using an ELISA method.https://www.mdpi.com/2075-4418/11/4/698COVID-19SARS-CoV-2ELISAcytosalivary sampling |
spellingShingle | Marina Di Domenico Alfredo De Rosa Mariarosaria Boccellino Detection of SARS-COV-2 Proteins Using an ELISA Test Diagnostics COVID-19 SARS-CoV-2 ELISA cytosalivary sampling |
title | Detection of SARS-COV-2 Proteins Using an ELISA Test |
title_full | Detection of SARS-COV-2 Proteins Using an ELISA Test |
title_fullStr | Detection of SARS-COV-2 Proteins Using an ELISA Test |
title_full_unstemmed | Detection of SARS-COV-2 Proteins Using an ELISA Test |
title_short | Detection of SARS-COV-2 Proteins Using an ELISA Test |
title_sort | detection of sars cov 2 proteins using an elisa test |
topic | COVID-19 SARS-CoV-2 ELISA cytosalivary sampling |
url | https://www.mdpi.com/2075-4418/11/4/698 |
work_keys_str_mv | AT marinadidomenico detectionofsarscov2proteinsusinganelisatest AT alfredoderosa detectionofsarscov2proteinsusinganelisatest AT mariarosariaboccellino detectionofsarscov2proteinsusinganelisatest |