Dissecting the functions of cancer-associated fibroblasts to therapeutically target head and neck cancer microenvironment

Dissecting the functions of cancer-associated fibroblasts to therapeutically target head and neck cancer microenvironment

Head and neck cancers (HNC) are a diverse group of aggressive malignancies with high morbidity and mortality, leading to almost half-million deaths annually worldwide. A better understanding of the molecular processes governing tumor formation and progression is crucial to improve current diagnostic...

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Bibliographic Details
Main Authors: Llara Prieto-Fernández, Irene Montoro-Jiménez, Beatriz de Luxan-Delgado, María Otero-Rosales, Juan P. Rodrigo, Fernando Calvo, Juana M. García-Pedrero, Saúl Álvarez-Teijeiro
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Head and neck cancer
Tumor microenvironment
Cancer hallmarks
Fibroblast
CAFs
CAFs-based therapies
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223002901

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