Chikungunya virus infection disrupts MHC-I antigen presentation via nonstructural protein 2.
Infection by chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes severe polyarthralgia and polymyalgia, which can last in some people for months to years. Chronic CHIKV disease signs and symptoms are associated with the persistence of viral nucleic acid and antigen in tissues. Like humans...
Main Authors: | Brian C Ware, M Guston Parks, Mariana O L da Silva, Thomas E Morrison |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-03-01
|
Series: | PLoS Pathogens |
Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011794&type=printable |
Similar Items
-
Chikungunya virus: Molecular epidemiology of nonstructural proteins in Pakistan.
by: Nazish Badar, et al.
Published: (2021-01-01) -
Chikungunya virus nonstructural protein 1 is a versatile RNA capping and decapping enzyme
by: Law, Michelle Cheok Yien, et al.
Published: (2024) -
Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1
by: Zhang, Kuo, et al.
Published: (2022) -
IBV QX affects the antigen presentation function of BMDCs through nonstructural protein16
by: Yaotang Wu, et al.
Published: (2023-05-01) -
In silico analysis of natural compounds targeting structural and nonstructural proteins of chikungunya virus [version 2; referees: 2 approved]
by: Jaspreet Jain, et al.
Published: (2017-12-01)