HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

Abstract Accumulating evidence shows HOOK1 disordered in human malignancies. However, the clinicopathological and biological significance of HOOK1 in renal cell carcinoma (RCC) remains rarely studied. In this study, the authors demonstrate that HOOK1 is downregulated in RCC samples with predicted po...

Full description

Bibliographic Details
Main Authors:	Lei Yin, Wenjia Li, Xuxiao Chen, Ronghao Wang, Tao Zhang, Jialin Meng, Zhao Li, Li Xu, Rui Yin, Bo Cheng, Huan Yang
Format:	Article
Language:	English
Published:	Wiley 2023-06-01
Series:	Advanced Science
Subjects:	HOOK1 renal cell carcinoma TGF‐Î2 signaling TNFSF13B tumor metastasis
Online Access:	https://doi.org/10.1002/advs.202206955

Similar Items

TNFSF13 Is a Novel Onco-Inflammatory Marker and Correlates With Immune Infiltration in Gliomas
by: Rui Chen, et al.
Published: (2021-10-01)

Clinical Significance and Advances of TNFSF15 Modulation on Tumor Angiogenesis and Lymphangiogenesis
by: QIN Tingting, et al.
Published: (2020-07-01)

Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway
by: Zhang H, et al.
Published: (2023-11-01)

Molecular Characterization, Evolution and Expression Analysis of TNFSF14 and Three TNFSF Receptors in Spotted Gar <i>Lepisosteus oculatus</i>
by: Yaxin Wu, et al.
Published: (2022-07-01)

Analysis of TNFSF13B polymorphisms and BAFF expression in rheumatoid arthritis and primary Sjögren's syndrome patients
by: Enrique Santillán‐López, et al.
Published: (2022-06-01)

Associations between TNFSF13B polymorphisms and primary Sjögren's syndrome susceptibility in primary Sjögren's syndrome patients: A meta‐analysis
by: Anhao Zheng, et al.
Published: (2023-12-01)

Overexpression of TNFSF11 reduces GPX4 levels and increases sensitivity to ferroptosis inducers in lung adenocarcinoma
by: Zizhen Li, et al.
Published: (2024-04-01)

LIGHT/TNFSF14 Affects Adipose Tissue Phenotype
by: Angela Oranger, et al.
Published: (2024-01-01)

Identification of the role of autophagy-related TNFSF10/ hsa-let-7a-5p axis in vitiligo development and potential herbs exploring based on a bioinformatics analysis
by: Wenwen Wang, et al.
Published: (2023-12-01)

Association of Common Variants of <i>TNFSF13</i> and <i>TNFRSF13B</i> Genes with CLL Risk and Clinical Picture, as Well as Expression of Their Products—APRIL and TACI Molecules
by: Monika Jasek, et al.
Published: (2020-10-01)

Molecular and Clinical Characterization of LIGHT/TNFSF14 Expression at Transcriptional Level via 998 Samples With Brain Glioma
by: Ying Yang, et al.
Published: (2021-08-01)

BONE DENSITOMETRY INDICATORS IN POSTMENOPAUSAL WOMEN DEPENDING ON TNFSF11 GENE RS9594738 (C>T) POLYMORPHISM
by: E. A. MAYLYAN
Published: (2017-06-01)

TNFSF15 facilitates the differentiation of CD11b+ myeloid cells into vascular pericytes in tumors
by: Xiangxiang Gu, et al.
Published: (2023-11-01)

Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14)
by: Andrea Herrero-Cervera, et al.
Published: (2021-10-01)

Glucocorticoid Receptor Regulates <i>TNFSF11</i> Transcription by Binding to Glucocorticoid Responsive Element in <i>TNFSF11</i> Proximal Promoter Region
by: Nika Lovšin, et al.
Published: (2021-01-01)

TNFSF14-Derived Molecules as a Novel Treatment for Obesity and Type 2 Diabetes
by: Mark Agostino, et al.
Published: (2021-09-01)

BCMA (TNFRSF17) Induces APRIL and BAFF Mediated Breast Cancer Cell Stemness
by: Vasiliki Pelekanou, et al.
Published: (2018-08-01)

Plasma TNFSF10 levels associated with acamprosate treatment response in patients with alcohol use disorder
by: Ming-Fen Ho, et al.
Published: (2022-09-01)

Mild steel forged ramshorn hooks
by: 8096 British Standards Institution
Published: (1958)

TNFSF14: LIGHTing the Way for Effective Cancer Immunotherapy
by: Joseph G. Skeate, et al.
Published: (2020-05-01)

Hooks for lifting freight containers of up to 30 tonnes
by: 8096 British Standards Institution

Access hooks for chimneys and other high structures in steel
by: 8096 British Standards Institution
Published: (1972)

Genetic Association of rs1021188 and DNA Methylation Signatures of TNFSF11 in the Risk of Conductive Hearing Loss
by: Amal Bouzid, et al.
Published: (2022-04-01)

Circle hook versus J-hook: A case study of the Sultanate of Oman
by: Ibrahim A. Al-Qartoubi, et al.
Published: (2019-01-01)

Higher tensile steel hooks for chains, slings, blocks and general engineering purposes
by: 8096 British Standards Institution

Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs in HMMR as Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients
by: Behzad Bidadi, et al.
Published: (2018-03-01)

Editorial: The Tumor Necrosis Factor Superfamily: An Increasing Role in Breast Cancer
by: Dirk Geerts, et al.
Published: (2020-12-01)

The Influence of Hypertensive Therapies on Circulating Factors: Clinical Implications for SCFAs, FGF21, TNFSF14 and TNF-α
by: Aaron L. Magno, et al.
Published: (2020-08-01)

Treble-swivel cargo hooks for ships union purchase
by: 8096 British Standards Institution

The influence of hook tip in different depths on the acromioclavicular joint dislocation treated with clavicular hook plate: A retrospective study
by: Ding Xu, et al.
Published: (2021-11-01)

Drawbars and towing hooks on agricultural tractors
by: 8096 British Standards Institution

TNFSF14, a novel target of miR‐326, facilitates airway remodeling in airway smooth muscle cells via inducing extracellular matrix protein deposition and proliferation
by: Hui Zhang, et al.
Published: (2020-07-01)

LIGHT/TNFSF14 as a New Biomarker of Bone Disease in Multiple Myeloma Patients Experiencing Therapeutic Regimens
by: Giacomina Brunetti, et al.
Published: (2018-10-01)

Artemisinin relieves osteoarthritis by activating mitochondrial autophagy through reducing TNFSF11 expression and inhibiting PI3K/AKT/mTOR signaling in cartilage
by: Jin Li, et al.
Published: (2022-07-01)

TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway
by: Laura D’Ignazio, et al.
Published: (2018-08-01)

A novel L-phenylalanine dipeptide inhibits prostate cancer cell proliferation by targeting TNFSF9
by: Di Zhang, et al.
Published: (2023-04-01)

The association of TRAP1 gene and TNFSF4 gene polymorphisms with susceptibility of rheumatoid arthritis in a sample of Egyptian patients
by: Alshaymaa A Ibrahim, et al.
Published: (2023-01-01)

Non-linear torsional oscillation of a system incorporating a Hooke's joint /
by: 285876 Porter, B., et al.

Case Report: In Situ Expression of a Proliferation-Inducing Ligand in Neuromyelitis Optica
by: Laurie Baert, et al.
Published: (2021-08-01)

Application of a new sternoclavicular hook plate in bipolar clavicle injuries
by: Han Zhang, et al.
Published: (2023-01-01)