Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia.

Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia.

<h4>Background</h4>Cell-free foetal haemoglobin (HbF) has been shown to play a role in the pathology of preeclampsia (PE). In the present study, we aimed to further characterize the harmful effects of extracellular free haemoglobin (Hb) on the placenta. In particular, we investigated whe...

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Bibliographic Details
Main Authors: Tina Cronqvist, Karen Saljé, Mary Familari, Seth Guller, Henning Schneider, Chris Gardiner, Ian L Sargent, Christopher W Redman, Matthias Mörgelin, Bo Åkerström, Magnus Gram, Stefan R Hansson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090020&type=printable

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