Enhanced Bacitracin Production by Systematically Engineering S-Adenosylmethionine Supply Modules in Bacillus licheniformis

Enhanced Bacitracin Production by Systematically Engineering S-Adenosylmethionine Supply Modules in Bacillus licheniformis

Bacitracin is a broad-spectrum veterinary antibiotic that widely used in the fields of veterinary drug and feed additive. S-Adenosylmethionine (SAM) is a critical factor involved in many biochemical reactions, especially antibiotic production. However, whether SAM affects bacitracin synthesis is sti...

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Bibliographic Details
Main Authors: Dongbo Cai, Bowen Zhang, Jiang Zhu, Haixia Xu, Pei Liu, Zhi Wang, Junhui Li, Zhifan Yang, Xin Ma, Shouwen Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bacitracin
S-Adenosylmethionine
Bacillus licheniformis
methionine
metabolic engineering
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00305/full

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