Pre-Clinical Investigations of the Pharmacodynamics of Immunogenic Smart Radiotherapy Biomaterials (iSRB)

Pre-Clinical Investigations of the Pharmacodynamics of Immunogenic Smart Radiotherapy Biomaterials (iSRB)

The use of an immunogenic smart radiotherapy biomaterial (iSRB) for the delivery of anti-CD40 is effective in treating different cancers in animal models. This study further characterizes the use of iSRBs to evaluate any associated toxicity in healthy C57BL6 mice. iSRBs were fabricated using a poly-...

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Bibliographic Details
Main Authors: Michele Moreau, Shahinur Acter, Lindokuhle M. Ngema, Noella Bih, Gnagna Sy, Lensa S. Keno, Kwok Fan Chow, Erno Sajo, Oscar Nebangwa, Jacques Walker, Philmo Oh, Eric Broyles, Wilfred Ngwa, Sayeda Yasmin-Karim
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
anti-CD40 monoclonal antibody
smart radiotherapy biomaterials
toxicity
hematology
histopathology
clinical chemistry
Online Access:https://www.mdpi.com/1999-4923/15/12/2778

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