FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity

FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity

Genetically encoded calcium indicators (GECIs) have become a widespread tool for the visualization of neuronal activity. As compared to popular GCaMP GECIs, the FGCaMP indicator benefits from calmodulin and M13-peptide from the fungi <i>Aspergillus niger</i> and <i>Aspergillus fumi...

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Bibliographic Details
Main Authors: Natalia V. Barykina, Vladimir P. Sotskov, Anna M. Gruzdeva, You Kure Wu, Ruben Portugues, Oksana M. Subach, Elizaveta S. Chefanova, Viktor V. Plusnin, Olga I. Ivashkina, Konstantin V. Anokhin, Anna V. Vlaskina, Dmitry A. Korzhenevskiy, Alena Y. Nikolaeva, Konstantin M. Boyko, Tatiana V. Rakitina, Anna M. Varizhuk, Galina E. Pozmogova, Fedor V. Subach
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
calcium imaging
genetically encoded calcium indicator
protein engineering
crystal structure
FGCaMP7
FGCaMP
Online Access:https://www.mdpi.com/1422-0067/21/8/3012

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