Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate
Four new metabolites, including three new oblongolides named C1, P1, and X1 (1-3) and 6-hydroxyphomodiol (10), along with eight known compounds – oblongolides B (4), C (5), D (6), O (7), P (8) and U (9), (3R,4aR,5S,6R)-6-hydroxy-5-methylramulosin (11), and (3R)-5-methylmellein (12) – were isolated f...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-04-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/16/4/3351/ |
| _version_ | 1818009486335410176 |
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| author | Hai Feng Chen Xiao Kun Zhang Quan Cheng Chen Zhi Yu Hu Xiang Lin Ting Lin Guang Hui Wang Yang Xu |
| author_facet | Hai Feng Chen Xiao Kun Zhang Quan Cheng Chen Zhi Yu Hu Xiang Lin Ting Lin Guang Hui Wang Yang Xu |
| author_sort | Hai Feng Chen |
| collection | DOAJ |
| description | Four new metabolites, including three new oblongolides named C1, P1, and X1 (1-3) and 6-hydroxyphomodiol (10), along with eight known compounds – oblongolides B (4), C (5), D (6), O (7), P (8) and U (9), (3R,4aR,5S,6R)-6-hydroxy-5-methylramulosin (11), and (3R)-5-methylmellein (12) – were isolated from the endophytic fungal strain Phomopsis sp. XZ-01 of Camptotheca acuminate. Their structures were elucidated by spectroscopic analyses, including 1H- and 13C-NMR, 2D NMR (HSQC, HMBC, 1H-1H COSY and NOESY) and HR-FT-MS. Cytotoxic activities of these compounds were evaluated. Some of them showed weak selective activities. |
| first_indexed | 2024-04-14T05:43:27Z |
| format | Article |
| id | doaj.art-dc260aab015a4a0cb03ff6d5bfae41f5 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-14T05:43:27Z |
| publishDate | 2011-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-dc260aab015a4a0cb03ff6d5bfae41f52022-12-22T02:09:22ZengMDPI AGMolecules1420-30492011-04-011643351335910.3390/molecules16043351Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminateHai Feng ChenXiao Kun ZhangQuan Cheng ChenZhi Yu HuXiang LinTing LinGuang Hui WangYang XuFour new metabolites, including three new oblongolides named C1, P1, and X1 (1-3) and 6-hydroxyphomodiol (10), along with eight known compounds – oblongolides B (4), C (5), D (6), O (7), P (8) and U (9), (3R,4aR,5S,6R)-6-hydroxy-5-methylramulosin (11), and (3R)-5-methylmellein (12) – were isolated from the endophytic fungal strain Phomopsis sp. XZ-01 of Camptotheca acuminate. Their structures were elucidated by spectroscopic analyses, including 1H- and 13C-NMR, 2D NMR (HSQC, HMBC, 1H-1H COSY and NOESY) and HR-FT-MS. Cytotoxic activities of these compounds were evaluated. Some of them showed weak selective activities.http://www.mdpi.com/1420-3049/16/4/3351/Camptotheca acuminateendophytic fungusPhomopsis sp. XZ-01oblongolidesnew metabolites |
| spellingShingle | Hai Feng Chen Xiao Kun Zhang Quan Cheng Chen Zhi Yu Hu Xiang Lin Ting Lin Guang Hui Wang Yang Xu Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate Molecules Camptotheca acuminate endophytic fungus Phomopsis sp. XZ-01 oblongolides new metabolites |
| title | Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate |
| title_full | Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate |
| title_fullStr | Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate |
| title_full_unstemmed | Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate |
| title_short | Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate |
| title_sort | three new oblongolides from phomopsis sp xz 01 an endophytic fungus from camptotheca acuminate |
| topic | Camptotheca acuminate endophytic fungus Phomopsis sp. XZ-01 oblongolides new metabolites |
| url | http://www.mdpi.com/1420-3049/16/4/3351/ |
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