Three-Dimensional Structures of Carbohydrates and Where to Find Them
Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/20/7702 |
| _version_ | 1797550622910709760 |
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| author | Sofya I. Scherbinina Philip V. Toukach |
| author_facet | Sofya I. Scherbinina Philip V. Toukach |
| author_sort | Sofya I. Scherbinina |
| collection | DOAJ |
| description | Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbohydrates breaks new ground in modern glycoscience. This review is dedicated to approaches of chemo- and glyco-informatics towards 3D structural data generation, deposition and processing in regard to carbohydrates and their derivatives. Databases, molecular modeling and experimental data validation services, and structure visualization facilities developed for last five years are reviewed. |
| first_indexed | 2024-03-10T15:31:56Z |
| format | Article |
| id | doaj.art-dc28b62c175e4a848d441a59c9e24842 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T15:31:56Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-dc28b62c175e4a848d441a59c9e248422023-11-20T17:34:21ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-10-012120770210.3390/ijms21207702Three-Dimensional Structures of Carbohydrates and Where to Find ThemSofya I. Scherbinina0Philip V. Toukach1N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninsky prospect 47, 119991 Moscow, RussiaN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninsky prospect 47, 119991 Moscow, RussiaAnalysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbohydrates breaks new ground in modern glycoscience. This review is dedicated to approaches of chemo- and glyco-informatics towards 3D structural data generation, deposition and processing in regard to carbohydrates and their derivatives. Databases, molecular modeling and experimental data validation services, and structure visualization facilities developed for last five years are reviewed.https://www.mdpi.com/1422-0067/21/20/7702carbohydratespatial structuremodel builddatabaseweb-toolglycoinformatics |
| spellingShingle | Sofya I. Scherbinina Philip V. Toukach Three-Dimensional Structures of Carbohydrates and Where to Find Them International Journal of Molecular Sciences carbohydrate spatial structure model build database web-tool glycoinformatics |
| title | Three-Dimensional Structures of Carbohydrates and Where to Find Them |
| title_full | Three-Dimensional Structures of Carbohydrates and Where to Find Them |
| title_fullStr | Three-Dimensional Structures of Carbohydrates and Where to Find Them |
| title_full_unstemmed | Three-Dimensional Structures of Carbohydrates and Where to Find Them |
| title_short | Three-Dimensional Structures of Carbohydrates and Where to Find Them |
| title_sort | three dimensional structures of carbohydrates and where to find them |
| topic | carbohydrate spatial structure model build database web-tool glycoinformatics |
| url | https://www.mdpi.com/1422-0067/21/20/7702 |
| work_keys_str_mv | AT sofyaischerbinina threedimensionalstructuresofcarbohydratesandwheretofindthem AT philipvtoukach threedimensionalstructuresofcarbohydratesandwheretofindthem |