Childhood brain tumors in Southern Nigeria: A multicenter experience
Background: Childhood brain tumors (CBTs) constitute 5% of all childhood tumors and can involve any part of the brain disrupting brain structure, form, and function with associated high morbidity and mortality. The objectives of the study were to determine the clinicopathologic pattern and treatment...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | International Journal of Medicine and Health Development |
| Subjects: | |
| Online Access: | http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2021;volume=26;issue=2;spage=128;epage=134;aulast=Uwaezuoke |
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| author | Ndubuisi Anyele Uwaezuoke Enoch Ogbonna Uche Christian B Eke Ann Ebele Aronu Francis I Ukekwe Joy N Eze Ngozi Ojinnaka |
| author_facet | Ndubuisi Anyele Uwaezuoke Enoch Ogbonna Uche Christian B Eke Ann Ebele Aronu Francis I Ukekwe Joy N Eze Ngozi Ojinnaka |
| author_sort | Ndubuisi Anyele Uwaezuoke |
| collection | DOAJ |
| description | Background: Childhood brain tumors (CBTs) constitute 5% of all childhood tumors and can involve any part of the brain disrupting brain structure, form, and function with associated high morbidity and mortality. The objectives of the study were to determine the clinicopathologic pattern and treatment outcome of brain tumor in children in our setting. Materials and Methods: A 3-year prospective multicenter observational study of children with brain tumors was undertaken. Relevant patients’ clinical data sought, included histological diagnosis, World Health Organization grade and survival pattern. Data were analyzed using SPSS version 21.0, whereas the level of statistical significance was set at P < 0.05. Results: Study participants were aged 2–16 (mean 7.93 ± 4.21) years. Fifteen were female (51.7%). The duration between; illness to presentation, presentation to confirmation of diagnosis, and from presentation to specific treatment were 4.40 ± 4.40, 5.0 ± 4.0, and 6.3 ± 6.0 months, respectively.Cerebellar tumors occurred most commonly 15 (51.7%). Majority of the cases, 21 (72.4%) were low grade. Central nervous tumor was first suspected in eight cases (27.6%) at the referring center. Eleven (37.9%) and ten (34.5%) patients, respectively, survived at 1 year and 3 years of follow-up post-diagnosis. The most common complication was hydrocephalus 12(41.4%). Mortality occurred in seven (21.4%) patients arising from their brain tumors. Conclusion: Poor knowledge of health care providers in referring centers, along with delay in initiating treatment contributed to mortality and morbidity. |
| first_indexed | 2024-04-12T07:48:15Z |
| format | Article |
| id | doaj.art-dc2e7c55fe174dfd836f2b4283f71a15 |
| institution | Directory Open Access Journal |
| issn | 2635-3695 |
| language | English |
| last_indexed | 2024-04-12T07:48:15Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Medicine and Health Development |
| spelling | doaj.art-dc2e7c55fe174dfd836f2b4283f71a152022-12-22T03:41:39ZengWolters Kluwer Medknow PublicationsInternational Journal of Medicine and Health Development2635-36952021-01-0126212813410.4103/ijmh.IJMH_24_20Childhood brain tumors in Southern Nigeria: A multicenter experienceNdubuisi Anyele UwaezuokeEnoch Ogbonna UcheChristian B EkeAnn Ebele AronuFrancis I UkekweJoy N EzeNgozi OjinnakaBackground: Childhood brain tumors (CBTs) constitute 5% of all childhood tumors and can involve any part of the brain disrupting brain structure, form, and function with associated high morbidity and mortality. The objectives of the study were to determine the clinicopathologic pattern and treatment outcome of brain tumor in children in our setting. Materials and Methods: A 3-year prospective multicenter observational study of children with brain tumors was undertaken. Relevant patients’ clinical data sought, included histological diagnosis, World Health Organization grade and survival pattern. Data were analyzed using SPSS version 21.0, whereas the level of statistical significance was set at P < 0.05. Results: Study participants were aged 2–16 (mean 7.93 ± 4.21) years. Fifteen were female (51.7%). The duration between; illness to presentation, presentation to confirmation of diagnosis, and from presentation to specific treatment were 4.40 ± 4.40, 5.0 ± 4.0, and 6.3 ± 6.0 months, respectively.Cerebellar tumors occurred most commonly 15 (51.7%). Majority of the cases, 21 (72.4%) were low grade. Central nervous tumor was first suspected in eight cases (27.6%) at the referring center. Eleven (37.9%) and ten (34.5%) patients, respectively, survived at 1 year and 3 years of follow-up post-diagnosis. The most common complication was hydrocephalus 12(41.4%). Mortality occurred in seven (21.4%) patients arising from their brain tumors. Conclusion: Poor knowledge of health care providers in referring centers, along with delay in initiating treatment contributed to mortality and morbidity.http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2021;volume=26;issue=2;spage=128;epage=134;aulast=Uwaezuokechildhood brain tumoroutcomespresentation |
| spellingShingle | Ndubuisi Anyele Uwaezuoke Enoch Ogbonna Uche Christian B Eke Ann Ebele Aronu Francis I Ukekwe Joy N Eze Ngozi Ojinnaka Childhood brain tumors in Southern Nigeria: A multicenter experience International Journal of Medicine and Health Development childhood brain tumor outcomes presentation |
| title | Childhood brain tumors in Southern Nigeria: A multicenter experience |
| title_full | Childhood brain tumors in Southern Nigeria: A multicenter experience |
| title_fullStr | Childhood brain tumors in Southern Nigeria: A multicenter experience |
| title_full_unstemmed | Childhood brain tumors in Southern Nigeria: A multicenter experience |
| title_short | Childhood brain tumors in Southern Nigeria: A multicenter experience |
| title_sort | childhood brain tumors in southern nigeria a multicenter experience |
| topic | childhood brain tumor outcomes presentation |
| url | http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2021;volume=26;issue=2;spage=128;epage=134;aulast=Uwaezuoke |
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