AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors

The authors develop a quantitative description of alternating current amplification gain in organic electrochemical transistors. The findings are applied to achieve detection of single glioblastoma cell adhesion with 20 dB gain compared to microelectrodes.

Bibliographic Details
Main Authors: Filippo Bonafè, Francesco Decataldo, Isabella Zironi, Daniel Remondini, Tobias Cramer, Beatrice Fraboni
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33094-2
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author Filippo Bonafè
Francesco Decataldo
Isabella Zironi
Daniel Remondini
Tobias Cramer
Beatrice Fraboni
author_facet Filippo Bonafè
Francesco Decataldo
Isabella Zironi
Daniel Remondini
Tobias Cramer
Beatrice Fraboni
author_sort Filippo Bonafè
collection DOAJ
description The authors develop a quantitative description of alternating current amplification gain in organic electrochemical transistors. The findings are applied to achieve detection of single glioblastoma cell adhesion with 20 dB gain compared to microelectrodes.
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spelling doaj.art-dc2f8882fab2476fa82e73b7c54405fc2022-12-22T04:30:24ZengNature PortfolioNature Communications2041-17232022-09-011311910.1038/s41467-022-33094-2AC amplification gain in organic electrochemical transistors for impedance-based single cell sensorsFilippo Bonafè0Francesco Decataldo1Isabella Zironi2Daniel Remondini3Tobias Cramer4Beatrice Fraboni5Department of Physics and Astronomy, University of BolognaDepartment of Physics and Astronomy, University of BolognaDepartment of Physics and Astronomy, University of BolognaDepartment of Physics and Astronomy, University of BolognaDepartment of Physics and Astronomy, University of BolognaDepartment of Physics and Astronomy, University of BolognaThe authors develop a quantitative description of alternating current amplification gain in organic electrochemical transistors. The findings are applied to achieve detection of single glioblastoma cell adhesion with 20 dB gain compared to microelectrodes.https://doi.org/10.1038/s41467-022-33094-2
spellingShingle Filippo Bonafè
Francesco Decataldo
Isabella Zironi
Daniel Remondini
Tobias Cramer
Beatrice Fraboni
AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors
Nature Communications
title AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors
title_full AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors
title_fullStr AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors
title_full_unstemmed AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors
title_short AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors
title_sort ac amplification gain in organic electrochemical transistors for impedance based single cell sensors
url https://doi.org/10.1038/s41467-022-33094-2
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AT tobiascramer acamplificationgaininorganicelectrochemicaltransistorsforimpedancebasedsinglecellsensors
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