T4 reduces cisplatin resistance by inhibiting AEG-1 gene expression in lung cancer cells

Abstract Lung cancer is the most malignant form of cancer and has the highest morbidity and mortality worldwide. Due to drug resistance, the current chemotherapy for lung cancer is not effective and has poor therapeutic effects. Tripchlorolide (T4), a natural extract from the plant Tripterygium wilf...

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Bibliographic Details
Main Authors: Tian-jiao Song, Xiao-hong Lin, Ping-ting Huang, Yu-qing Chen, Li-min Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15643-3

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