Targeting IRE1α and PERK in the endoplasmic reticulum stress pathway attenuates fatty acid-induced insulin resistance in bovine hepatocytes
ABSTRACT: Endoplasmic reticulum (ER) stress can be induced by various stimuli and triggers the unfolded protein response to activate intracellular signaling pathways that are mediated by 3 ER-resident sensors: inositol requiring protein-1α (IRE1α), PKR-like ER kinase (PERK), and activating transcrip...
| Main Authors: | , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Elsevier
2022-08-01
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| 丛编: | Journal of Dairy Science |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S0022030222003770 |