Alterations in Malondiadehyde and membrane potential in anaemic patients
Background: Anaemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood and has a lowered ability of the blood to carry oxygen. Aim and Objectives: To determine the level of Malondiadehyde and membrane potential in anaemic patients attending General Hospital Owerri...
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| Format: | Article |
| Language: | English |
| Published: |
Al Ameen Medical College
2017-10-01
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| Series: | Al Ameen Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://ajms.alameenmedical.org/ArticlePDFs/12%20AJMS%20V10.N4.2017%20p%20281-283.pdf |
| _version_ | 1819042373488869376 |
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| author | Somtochukwu Mercy Onwuagba Nnodim Johnkennedy |
| author_facet | Somtochukwu Mercy Onwuagba Nnodim Johnkennedy |
| author_sort | Somtochukwu Mercy Onwuagba |
| collection | DOAJ |
| description | Background: Anaemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood and has a lowered ability of the blood to carry oxygen. Aim and Objectives: To determine the level of Malondiadehyde and membrane potential in anaemic patients attending General Hospital Owerri. Materials and methods: Fifty confirmed anaemicc patients and fifty apparently healthy subjects (control) between the ages of 10 to 20 years were selected in this study. Serum malondialdehyde (MDA) and membrane potential were estimated using standard methods. Results: There serum levels of MDA was significantly increased in anaemic patients when compared to control (p<0.05). While the membrane potential was significantly decreased in anaemic patients when compared with the control (P< 0.05). Conclusion: These could probably imply that anaemic patients could be prone to oxidative stress as well as have low cell activity. |
| first_indexed | 2024-12-21T09:39:52Z |
| format | Article |
| id | doaj.art-dc36c74675bb42c3be9127b4f3b8b5a7 |
| institution | Directory Open Access Journal |
| issn | 0974-1143 0974-1143 |
| language | English |
| last_indexed | 2024-12-21T09:39:52Z |
| publishDate | 2017-10-01 |
| publisher | Al Ameen Medical College |
| record_format | Article |
| series | Al Ameen Journal of Medical Sciences |
| spelling | doaj.art-dc36c74675bb42c3be9127b4f3b8b5a72022-12-21T19:08:30ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11430974-11432017-10-011004281283Alterations in Malondiadehyde and membrane potential in anaemic patientsSomtochukwu Mercy Onwuagba0Nnodim Johnkennedy1Department of Public Health, School of Health Technology, Federal University of Technology Owerri Imo State, NigeriaDepartment of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State, NigeriaBackground: Anaemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood and has a lowered ability of the blood to carry oxygen. Aim and Objectives: To determine the level of Malondiadehyde and membrane potential in anaemic patients attending General Hospital Owerri. Materials and methods: Fifty confirmed anaemicc patients and fifty apparently healthy subjects (control) between the ages of 10 to 20 years were selected in this study. Serum malondialdehyde (MDA) and membrane potential were estimated using standard methods. Results: There serum levels of MDA was significantly increased in anaemic patients when compared to control (p<0.05). While the membrane potential was significantly decreased in anaemic patients when compared with the control (P< 0.05). Conclusion: These could probably imply that anaemic patients could be prone to oxidative stress as well as have low cell activity.http://ajms.alameenmedical.org/ArticlePDFs/12%20AJMS%20V10.N4.2017%20p%20281-283.pdfMalondiadehydeMembrane PotentialAnaemiaOwerri |
| spellingShingle | Somtochukwu Mercy Onwuagba Nnodim Johnkennedy Alterations in Malondiadehyde and membrane potential in anaemic patients Al Ameen Journal of Medical Sciences Malondiadehyde Membrane Potential Anaemia Owerri |
| title | Alterations in Malondiadehyde and membrane potential in anaemic patients |
| title_full | Alterations in Malondiadehyde and membrane potential in anaemic patients |
| title_fullStr | Alterations in Malondiadehyde and membrane potential in anaemic patients |
| title_full_unstemmed | Alterations in Malondiadehyde and membrane potential in anaemic patients |
| title_short | Alterations in Malondiadehyde and membrane potential in anaemic patients |
| title_sort | alterations in malondiadehyde and membrane potential in anaemic patients |
| topic | Malondiadehyde Membrane Potential Anaemia Owerri |
| url | http://ajms.alameenmedical.org/ArticlePDFs/12%20AJMS%20V10.N4.2017%20p%20281-283.pdf |
| work_keys_str_mv | AT somtochukwumercyonwuagba alterationsinmalondiadehydeandmembranepotentialinanaemicpatients AT nnodimjohnkennedy alterationsinmalondiadehydeandmembranepotentialinanaemicpatients |