[11C]SCH23390 binding to the D1-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis

[11C]SCH23390 binding to the D1-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis

Abstract Background The D1-dopamine receptor radioligand [11C]SCH23390 has been frequently used in PET studies. In drug-naïve patients with schizophrenia, the findings have been inconsistent, with decreases, increases, and no change in the frontal cortex D1-dopamine receptors. While these discrepanc...

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Bibliographic Details
Main Authors: Per Stenkrona, Granville J. Matheson, Simon Cervenka, Pontus Plavén Sigray, Christer Halldin, Lars Farde
Format: Article
Language:English
Published: SpringerOpen 2018-08-01
Series:EJNMMI Research
Subjects:
Positron emission tomography
ROI
Realignment
FreeSurfer
D1-dopamine receptor
Online Access:http://link.springer.com/article/10.1186/s13550-018-0416-2

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