IL-17RA promotes pathologic epithelial inflammation in a mouse model of upper respiratory influenza infection.

The upper respiratory tract (nasopharynx or NP) is the first site of influenza replication, allowing the virus to disseminate to the lower respiratory tract or promoting community transmission. The host response in the NP regulates an intricate balance between viral control and tissue pathology. The...

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Bibliographic Details
Main Authors: Zahrasadat Navaeiseddighi, Jitendra Kumar Tripathi, Kai Guo, Zhihan Wang, Taylor Schmit, Delano R Brooks, Reese A Allen, Junguk Hur, Ramkumar Mathur, Donald Jurivich, Nadeem Khan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011847&type=printable

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