Increased Development of Th1, Th17, and Th1.17 Cells Under T1 Polarizing Conditions in Juvenile Idiopathic Arthritis

Increased Development of Th1, Th17, and Th1.17 Cells Under T1 Polarizing Conditions in Juvenile Idiopathic Arthritis

In juvenile idiopathic arthritis (JIA) inflammatory T cells and their produced cytokines are drug targets and play a role in disease pathogenesis. Despite their clinical importance, the sources and types of inflammatory T cells involved remain unclear. T cells respond to polarizing factors to initia...

Full description

Bibliographic Details
Main Authors:	Anna E. Patrick, Kayla Shoaff, Tashawna Esmond, David M. Patrick, David K. Flaherty, T Brent Graham, Philip S. Crooke, Susan Thompson, Thomas M. Aune
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Immunology
Subjects:	juvenile idiopathic arthritis (JIA) interferon gamma (IFNγ) interleukin 17 (IL-17) T cell T helper cell (Th) Th1.17
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.848168/full

Similar Items

Distinct spatial and temporal roles for Th1, Th2, and Th17 cells in asthma
by: Weihang Luo, et al.
Published: (2022-08-01)

Identification of Th1-polarized Th17 cells: solving the problem
by: E. M. Kuklina, et al.
Published: (2023-06-01)

Markers of Th1 polarized Th17 cells (literature review)
by: E. M. Kuklina, et al.
Published: (2023-07-01)

ANALYSIS OF T HELPER SUBPOPULATIONS (Th1, Th2, Treg, Th17, ACTIVATED T-HELPERS) BY MEANS OF FLOW CYTOMETRY
by: S. V. Khaidukov, et al.
Published: (2014-07-01)

Differential Upregulation of Th1/Th17-Associated Proteins and PD-L1 in Granulomatous Mycosis Fungoides
by: Mario L. Marques-Piubelli, et al.
Published: (2024-02-01)

Curcumin as a regulator of Th17 cells: Unveiling the mechanisms
by: Ehsan Ghoushi, et al.
Published: (2024-07-01)

ROLE OF TH1 AND TH17 IMMUNE RESPONCES IN PATHOGENESIS OF MULTIPLE SCLEROSIS
by: Miloš Kostić
Published: (2010-12-01)

Th17/1 and ex-Th17 cells are detected in patients with polyarticular juvenile arthritis and increase following treatment
by: Stephanie Wood, et al.
Published: (2024-03-01)

Th17 Cells in Viral Infections—Friend or Foe?
by: Iury Amancio Paiva, et al.
Published: (2021-05-01)

Effects of Th17 and Treg cells with their balance on thyroid-associated ophthalmopathy
by: Ping Wang, et al.
Published: (2022-07-01)

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties
by: Chittappen K. Prajeeth, et al.
Published: (2017-10-01)

The immunomodulation role of Th17 and Treg in renal transplantation
by: Dan-Lei Huang, et al.
Published: (2023-02-01)

Pro-Tumor and Anti-Tumor Functions of IL-17 and of TH17 Cells in Tumor Microenvironment
by: Gulubova M., et al.
Published: (2016-10-01)

T helper cell responses in adult diarrheal patients following natural infection with enterotoxigenic Escherichia coli are primarily of the Th17 type
by: Marjahan Akhtar, et al.
Published: (2023-09-01)

Th1-Th17 Ratio as a New Insight in Rheumatoid Arthritis Disease
by: Hadi Bazzazi, et al.
Published: (2018-02-01)

Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients
by: Marie-Therese Holzer, et al.
Published: (2022-04-01)

The Effect of PEGylated Graphene Oxide Nanoparticles on the Th17-Polarization of Activated T Helpers
by: Svetlana Zamorina, et al.
Published: (2023-01-01)

Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy
by: Julia Loos, et al.
Published: (2020-11-01)

Th17/Treg Imbalance in Chronic Obstructive Pulmonary Disease: Clinical and Experimental Evidence
by: Juliana Dias Lourenço, et al.
Published: (2021-12-01)

Th17/Regulatory T-Cell Imbalance and Acute Kidney Injury in Patients with Sepsis
by: Xiao Zhou, et al.
Published: (2022-07-01)

Th17 and Th1 Lymphocytes in Oligoarticular Juvenile Idiopathic Arthritis
by: Laura Maggi, et al.
Published: (2019-03-01)

Th17/Treg Imbalance: Implications in Lung Inflammatory Diseases
by: Rony Thomas, et al.
Published: (2023-03-01)

T Helper (Th) Cell Profiles in Pregnancy and Recurrent Pregnancy Losses: Th1/Th2/Th9/Th17/Th22/Tfh Cells
by: Wenjuan Wang, et al.
Published: (2020-08-01)

The Th17/IL-17 Axis and Kidney Diseases, With Focus on Lupus Nephritis
by: Feliciano Chanana Paquissi, et al.
Published: (2021-09-01)

Inflammasome Contribution to the Activation of Th1, Th2, and Th17 Immune Responses
by: Ekaterina Martynova, et al.
Published: (2022-03-01)

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients
by: Zhiguo Peng, et al.
Published: (2023-11-01)

MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma
by: Zhifeng Chen, et al.
Published: (2022-10-01)

Inheritance-Specific Dysregulation of Th1- and Th17-Associated Cytokines in Alopecia Areata
by: Monica M. Van Acker, et al.
Published: (2023-08-01)

THE EVOLUTION OF UNDERSTANDING OF THE IMMUNE SYSTEM'S ROLE IN THE PATHOGENESIS OF INFLAMMATORY MYOCARDIAL DISEASES: TH17-MEDIATED IMMUNE MECHANISMS
by: N. R. Paleev, et al.
Published: (2014-02-01)

Th17/Treg homeostasis, but not Th1/Th2 homeostasis, is implicated in exacerbation of human bronchial asthma
by: Zou XL, et al.
Published: (2018-09-01)

An increased expression profile of Th9/IL-9 correlated with Th17/IL-17 in patients with immune thrombocytopenia
by: Jianlin Qiao, et al.
Published: (2017-04-01)

Lipoprotein(a) concentration and the blood content of INFγ-producing T-helpers 17 (Th17/1) in males with premature coronary artery disease
by: A. Yu. Filatova, et al.
Published: (2022-07-01)

Evaluating the inhibition of IL-17A and TNFα in a cartilage explant model cultured with Th17-derived cytokines
by: Solveig Skovlund Groen, et al.
Published: (2024-06-01)

IL-17 and Th17 cells in systemic sclerosis: a comprehensive review
by: Bălănescu Paul, et al.
Published: (2017-12-01)

The Role of Th17/IL-17 in the Pathogenesis of Primary Nephrotic Syndrome in Children
by: Li Wang, et al.
Published: (2013-09-01)

Relationship between Th17-mediated immunity and airway inflammation in childhood neutrophilic asthma
by: Qing Wei, et al.
Published: (2021-01-01)

Th17 Cells and IL-17 are Increased in Patients with Brain Metastases from the Primary Lung Cancer
by: Gaiping HE, et al.
Published: (2013-09-01)

IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology
by: Jasper F. Nies, et al.
Published: (2020-02-01)

HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis
by: Xiaofeng Zhu, et al.
Published: (2024-02-01)

Elevated Th17 cell proportion, related cytokines and mRNA expression level in patients with hypertension-mediated organ damage: a case control study
by: Zhuoqun Wang, et al.
Published: (2022-06-01)