Infantile inflammatory bowel disease in three Syrian infants: a case series
Abstract Background Inflammatory bowel diseases, consisting of Crohn’s disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders. Inflammatory bowel diseases begin rarely in infants. Approximately 25% of patients with inflammatory bowel diseases present before the age of 20 ...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13256-024-04456-9 |
| _version_ | 1797247298105769984 |
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| author | Afif Alshwaiki Ranim M. H. D. Samir Nakhal Ali Alakbar Nahle Hussein Hamdar Nafiza Martini Jaber Mahmod |
| author_facet | Afif Alshwaiki Ranim M. H. D. Samir Nakhal Ali Alakbar Nahle Hussein Hamdar Nafiza Martini Jaber Mahmod |
| author_sort | Afif Alshwaiki |
| collection | DOAJ |
| description | Abstract Background Inflammatory bowel diseases, consisting of Crohn’s disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders. Inflammatory bowel diseases begin rarely in infants. Approximately 25% of patients with inflammatory bowel diseases present before the age of 20 years. Very early-onset inflammatory bowel disease occurs before the age of 6 years; infantile inflammatory bowel diseases occurs before the age of 2 years, and is extremely rare in infants under 1 year of age. Case presentation Herein, we report a case series of 7-month-, 11-month-, and 12-month-old Syrian infants that presented with diarrhea, hematochezia, and pale appearance and were finally diagnosed with infantile inflammatory bowel disease and treated. Conclusions Early diagnosis and ruling out infantile inflammatory bowel diseases despite its rarity are recommended. Over and above that, new drugs such as vedolizumab, golimumab, and less invasive treatment methods should also be taken into consideration for better response and adequate remission with improved quality of life. |
| first_indexed | 2024-04-24T19:56:28Z |
| format | Article |
| id | doaj.art-dc46e7889ef546508d680dfd8a7f739b |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-24T19:56:28Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-dc46e7889ef546508d680dfd8a7f739b2024-03-24T12:21:44ZengBMCJournal of Medical Case Reports1752-19472024-03-011811610.1186/s13256-024-04456-9Infantile inflammatory bowel disease in three Syrian infants: a case seriesAfif Alshwaiki0Ranim M. H. D. Samir Nakhal1Ali Alakbar Nahle2Hussein Hamdar3Nafiza Martini4Jaber Mahmod5Faculty of Medicine, Damascus UniversityFaculty of Medicine, Damascus UniversityFaculty of Medicine, Damascus UniversityFaculty of Medicine, Damascus UniversityFaculty of Medicine, Damascus UniversityFaculty of Medicine, Damascus UniversityAbstract Background Inflammatory bowel diseases, consisting of Crohn’s disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders. Inflammatory bowel diseases begin rarely in infants. Approximately 25% of patients with inflammatory bowel diseases present before the age of 20 years. Very early-onset inflammatory bowel disease occurs before the age of 6 years; infantile inflammatory bowel diseases occurs before the age of 2 years, and is extremely rare in infants under 1 year of age. Case presentation Herein, we report a case series of 7-month-, 11-month-, and 12-month-old Syrian infants that presented with diarrhea, hematochezia, and pale appearance and were finally diagnosed with infantile inflammatory bowel disease and treated. Conclusions Early diagnosis and ruling out infantile inflammatory bowel diseases despite its rarity are recommended. Over and above that, new drugs such as vedolizumab, golimumab, and less invasive treatment methods should also be taken into consideration for better response and adequate remission with improved quality of life.https://doi.org/10.1186/s13256-024-04456-9Inflammatory bowel diseasesCrohn’s diseaseUlcerative colitisVery early-onset IBD (VEO-IBD)InfantsCase series |
| spellingShingle | Afif Alshwaiki Ranim M. H. D. Samir Nakhal Ali Alakbar Nahle Hussein Hamdar Nafiza Martini Jaber Mahmod Infantile inflammatory bowel disease in three Syrian infants: a case series Journal of Medical Case Reports Inflammatory bowel diseases Crohn’s disease Ulcerative colitis Very early-onset IBD (VEO-IBD) Infants Case series |
| title | Infantile inflammatory bowel disease in three Syrian infants: a case series |
| title_full | Infantile inflammatory bowel disease in three Syrian infants: a case series |
| title_fullStr | Infantile inflammatory bowel disease in three Syrian infants: a case series |
| title_full_unstemmed | Infantile inflammatory bowel disease in three Syrian infants: a case series |
| title_short | Infantile inflammatory bowel disease in three Syrian infants: a case series |
| title_sort | infantile inflammatory bowel disease in three syrian infants a case series |
| topic | Inflammatory bowel diseases Crohn’s disease Ulcerative colitis Very early-onset IBD (VEO-IBD) Infants Case series |
| url | https://doi.org/10.1186/s13256-024-04456-9 |
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