Zika virus-induced neuro-ocular pathology in immunocompetent mice correlates with anti-ganglioside autoantibodies

Zika virus-induced neuro-ocular pathology in immunocompetent mice correlates with anti-ganglioside autoantibodies

A severe consequence of adult Zika virus (ZIKV) infection is Guillain-Barré Syndrome (GBS), where autoreactive antibodies attack peripheral and central nervous systems (CNS) resulting in neuro-ocular pathology and fatal complications. During virally induced GBS, autoimmune brain demyelination and ma...

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Bibliographic Details
Main Authors: Jacob T. Beaver, Lisa K. Mills, Dominika Swieboda, Nadia Lelutiu, Edward S. Esser, Olivia Q. Antao, Eugenia Scountzou, Dahnide T. Williams, Nikolaos Papaioannou, Elizabeth Q. Littauer, Ioanna Skountzou
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
flavivirus
zika virus
auto-antibodies
neuro-ocular pathology
Online Access:http://dx.doi.org/10.1080/21645515.2020.1775459

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