Contemporary use of sentinel lymph node biopsy in the head and neck
Sentinel lymph node biopsy has become a well-established and commonplace practice in many oncologic disease sites as a means to stage the regional lymphatics, avoid unnecessary surgery and decrease patient morbidity. In the head and neck, its role is well established for cutaneous melanoma with prov...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-06-01
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| Series: | World Journal of Otorhinolaryngology-Head and Neck Surgery |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S209588111630018X |
| _version_ | 1828823241339174912 |
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| author | Nolan B. Seim Chadwick L. Wright Amit Agrawal |
| author_facet | Nolan B. Seim Chadwick L. Wright Amit Agrawal |
| author_sort | Nolan B. Seim |
| collection | DOAJ |
| description | Sentinel lymph node biopsy has become a well-established and commonplace practice in many oncologic disease sites as a means to stage the regional lymphatics, avoid unnecessary surgery and decrease patient morbidity. In the head and neck, its role is well established for cutaneous melanoma with proven fidelity and survival benefit. Its role in use for other sites such as oral cavity carcinoma continues to develop with promising results from several recent trials. Although not widely adopted, the potential benefits of sentinel lymph node biopsy in the management of oral cavity carcinoma are apparent. Refinements in technology and protocols including development of novel radiopharmaceutical tracers, routine incorporation of detailed anatomic imaging, increasing surgeon experience and development of new intraoperative identification aids will likely lead to improvements in the use and accuracy of this technique. Keywords: Oral cavity cancer, Sentinel lymph node, Head and neck cancer, Squamous cell carcinoma, Lymphoscintigraphy |
| first_indexed | 2024-12-12T13:31:17Z |
| format | Article |
| id | doaj.art-dc4ae100ee794e1fb8c2ce3375011b78 |
| institution | Directory Open Access Journal |
| issn | 2095-8811 |
| language | English |
| last_indexed | 2024-12-12T13:31:17Z |
| publishDate | 2016-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | World Journal of Otorhinolaryngology-Head and Neck Surgery |
| spelling | doaj.art-dc4ae100ee794e1fb8c2ce3375011b782022-12-22T00:23:04ZengWileyWorld Journal of Otorhinolaryngology-Head and Neck Surgery2095-88112016-06-0122117125Contemporary use of sentinel lymph node biopsy in the head and neckNolan B. Seim0Chadwick L. Wright1Amit Agrawal2Department of Otolaryngology-Head and Neck Surgery, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Wexner Medical Center, 4000 Eye and Ear Institute, 915 Olentangy River Road, Columbus, OH, 43210, USAWright Center of Innovation in Biomedical Imaging, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, 395 W, 12th Avenue, Rm. 430, Columbus, OH, 43210, USADepartment of Otolaryngology-Head and Neck Surgery, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Wexner Medical Center, 4000 Eye and Ear Institute, 915 Olentangy River Road, Columbus, OH, 43210, USA; Corresponding author. 320 West 10th Avenue, Rm B-215, Columbus, OH, 43210, USA. Tel.: +1 614 293 8073; fax: +1 614 293 3193.Sentinel lymph node biopsy has become a well-established and commonplace practice in many oncologic disease sites as a means to stage the regional lymphatics, avoid unnecessary surgery and decrease patient morbidity. In the head and neck, its role is well established for cutaneous melanoma with proven fidelity and survival benefit. Its role in use for other sites such as oral cavity carcinoma continues to develop with promising results from several recent trials. Although not widely adopted, the potential benefits of sentinel lymph node biopsy in the management of oral cavity carcinoma are apparent. Refinements in technology and protocols including development of novel radiopharmaceutical tracers, routine incorporation of detailed anatomic imaging, increasing surgeon experience and development of new intraoperative identification aids will likely lead to improvements in the use and accuracy of this technique. Keywords: Oral cavity cancer, Sentinel lymph node, Head and neck cancer, Squamous cell carcinoma, Lymphoscintigraphyhttp://www.sciencedirect.com/science/article/pii/S209588111630018X |
| spellingShingle | Nolan B. Seim Chadwick L. Wright Amit Agrawal Contemporary use of sentinel lymph node biopsy in the head and neck World Journal of Otorhinolaryngology-Head and Neck Surgery |
| title | Contemporary use of sentinel lymph node biopsy in the head and neck |
| title_full | Contemporary use of sentinel lymph node biopsy in the head and neck |
| title_fullStr | Contemporary use of sentinel lymph node biopsy in the head and neck |
| title_full_unstemmed | Contemporary use of sentinel lymph node biopsy in the head and neck |
| title_short | Contemporary use of sentinel lymph node biopsy in the head and neck |
| title_sort | contemporary use of sentinel lymph node biopsy in the head and neck |
| url | http://www.sciencedirect.com/science/article/pii/S209588111630018X |
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