Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study
Objectives: Our research investigated the relationship between childhood leukemia and breastfeeding in the P. R. of China. Methods: We conducted a retrospective case-control study from March 2008 to April 2017 at the Children’s Hospital of Zhejiang University, Zhejiang province, P. R. of China, whic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-01-01
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| Series: | Libyan Journal of Medicine |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/19932820.2018.1508273 |
| _version_ | 1818433465178128384 |
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| author | Zhen Gao Rui Wang Zhao-Xia Qin Ao Dong Chong-Bin Liu |
| author_facet | Zhen Gao Rui Wang Zhao-Xia Qin Ao Dong Chong-Bin Liu |
| author_sort | Zhen Gao |
| collection | DOAJ |
| description | Objectives: Our research investigated the relationship between childhood leukemia and breastfeeding in the P. R. of China. Methods: We conducted a retrospective case-control study from March 2008 to April 2017 at the Children’s Hospital of Zhejiang University, Zhejiang province, P. R. of China, which reviewed 958 children who had been diagnosed with leukemia in case group and 785 healthy children in control group. Data were obtained from medical records, and if the medical records were incomplete, we called mothers of children by phone to complete the data. Results: Breastfeeding reduces the risk of childhood leukemia; the effect is greater, if feeding continued for 7–9 months (p = 0.002). In addition, we suggest that some factors such as maternal age, smoking during pregnancy, abortion history, genetic factors, parents use of hair dye, and the history of using birth control pills before pregnancy can increase the risk of childhood leukemia. Conclusions: This study indicates that promoting breastfeeding for 7–9 months may help lower the childhood leukemia incidence. Our study firstly demonstrates that breastfeeding has protective effects against childhood leukemia in the P. R. of China. Abbreviations: ALL: Acute lymphocytic leukemia; AML: Acute myeloid leukemia |
| first_indexed | 2024-12-14T16:21:31Z |
| format | Article |
| id | doaj.art-dc4c8a567409468faf2cd47cbca8eaa3 |
| institution | Directory Open Access Journal |
| issn | 1993-2820 1819-6357 |
| language | English |
| last_indexed | 2024-12-14T16:21:31Z |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Libyan Journal of Medicine |
| spelling | doaj.art-dc4c8a567409468faf2cd47cbca8eaa32022-12-21T22:54:47ZengTaylor & Francis GroupLibyan Journal of Medicine1993-28201819-63572019-01-0114110.1080/19932820.2018.15082731508273Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control studyZhen Gao0Rui Wang1Zhao-Xia Qin2Ao Dong3Chong-Bin Liu4Huzhou UniversityHuzhou UniversityHuzhou UniversityChildren’s Hospital of Zhejiang UniversityHuzhou UniversityObjectives: Our research investigated the relationship between childhood leukemia and breastfeeding in the P. R. of China. Methods: We conducted a retrospective case-control study from March 2008 to April 2017 at the Children’s Hospital of Zhejiang University, Zhejiang province, P. R. of China, which reviewed 958 children who had been diagnosed with leukemia in case group and 785 healthy children in control group. Data were obtained from medical records, and if the medical records were incomplete, we called mothers of children by phone to complete the data. Results: Breastfeeding reduces the risk of childhood leukemia; the effect is greater, if feeding continued for 7–9 months (p = 0.002). In addition, we suggest that some factors such as maternal age, smoking during pregnancy, abortion history, genetic factors, parents use of hair dye, and the history of using birth control pills before pregnancy can increase the risk of childhood leukemia. Conclusions: This study indicates that promoting breastfeeding for 7–9 months may help lower the childhood leukemia incidence. Our study firstly demonstrates that breastfeeding has protective effects against childhood leukemia in the P. R. of China. Abbreviations: ALL: Acute lymphocytic leukemia; AML: Acute myeloid leukemiahttp://dx.doi.org/10.1080/19932820.2018.1508273childhood leukemiabreastfeedingp. r. chinaprotective effect |
| spellingShingle | Zhen Gao Rui Wang Zhao-Xia Qin Ao Dong Chong-Bin Liu Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study Libyan Journal of Medicine childhood leukemia breastfeeding p. r. china protective effect |
| title | Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study |
| title_full | Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study |
| title_fullStr | Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study |
| title_full_unstemmed | Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study |
| title_short | Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study |
| title_sort | protective effect of breastfeeding against childhood leukemia in zhejiang province p r china a retrospective case control study |
| topic | childhood leukemia breastfeeding p. r. china protective effect |
| url | http://dx.doi.org/10.1080/19932820.2018.1508273 |
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