Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
PurposeTo compare the predicted ablation depth (AD) with the postoperatively measured corneal ablation depth (postop-AD) at central, paracentral, and midperipheral locations using two rotating Scheimpflug analyzers and a Fourier-domain optical coherence tomographer in eyes that underwent femtosecond...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.907334/full |
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| author | Hao Chen Ziqian Wang Kunke Li Yiran Wang Xin Li Lan Du Meimin Lin Giacomo Savini Qinmei Wang Ayong Yu Sisi Chen |
| author_facet | Hao Chen Ziqian Wang Kunke Li Yiran Wang Xin Li Lan Du Meimin Lin Giacomo Savini Qinmei Wang Ayong Yu Sisi Chen |
| author_sort | Hao Chen |
| collection | DOAJ |
| description | PurposeTo compare the predicted ablation depth (AD) with the postoperatively measured corneal ablation depth (postop-AD) at central, paracentral, and midperipheral locations using two rotating Scheimpflug analyzers and a Fourier-domain optical coherence tomographer in eyes that underwent femtosecond laser-assisted LASIK (FS-LASIK).MethodsThe values of corneal thickness were measured preoperatively and postoperatively at one and three months. The difference between preoperative and postoperative was defined as postop-AD. Measurements were performed at the corneal vertex and mid-peripheral area. The mid-peripheral corneal thickness was measured at the superior, inferior, nasal, and temporal locations at a distance of 1.0 or 2.5 mm from the corneal vertex. The predicted AD was calculated by ORK-CAM software (Schwind eye tech-solutions GmbH, Kleinostheim, Germany), and the difference between the predicted AD and postop-AD was defined as Δ-AD. Paired t-test analysis was employed to evaluate the differences, agreement was assessed by the Bland-Altman method.ResultsForty-two eyes of 42 patients were investigated. At one month, the predicted AD in the central and paracentral areas was underestimated by the Pentacam HR (Oculus, Wetzlar, Germany), Sirius (Costruzione Strumenti Oftalmici, Florence, Italy) and RTVue OCT (Optovue Inc., Freemont, CA, United States), whereas Δ-AD was negative as established by all devices and predominantly statistically significant. The Δ-AD values approximated zero at three months. The mean difference of Δ-AD at three months at the corneal vertex was 0.67 ± 9.39 mm, −7.92 ± 9.05 mm and −1.36 ± 8.31 mm, respectively. The mid-peripheral measurements had positive values at one month and even more highly positive at three months (with statistically significant differences in most of the cases). The agreement between the predicted and postop-AD was moderate with all devices, but slightly better with RTVue.ConclusionThe predicted AD seems to be underestimated in the central and paracentral corneal area and overestimated in the mid-periphery.Translational RelevanceThe study could help to partly explain and prevent the refractive errors after FS-LASIK. |
| first_indexed | 2024-04-12T18:03:43Z |
| format | Article |
| id | doaj.art-dc524e05371947fead99f77bd173adb2 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-12T18:03:43Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-dc524e05371947fead99f77bd173adb22022-12-22T03:22:03ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-05-01910.3389/fmed.2022.907334907334Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCTHao Chen0Ziqian Wang1Kunke Li2Yiran Wang3Xin Li4Lan Du5Meimin Lin6Giacomo Savini7Qinmei Wang8Ayong Yu9Sisi Chen10School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaShenzhen Eye Hospital, Shenzhen Key Ophthalmic Laboratory, Jinan University, Shenzhen, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaIRCCS G.B. Bietti Foundation, Rome, ItalySchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaSchool of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, ChinaPurposeTo compare the predicted ablation depth (AD) with the postoperatively measured corneal ablation depth (postop-AD) at central, paracentral, and midperipheral locations using two rotating Scheimpflug analyzers and a Fourier-domain optical coherence tomographer in eyes that underwent femtosecond laser-assisted LASIK (FS-LASIK).MethodsThe values of corneal thickness were measured preoperatively and postoperatively at one and three months. The difference between preoperative and postoperative was defined as postop-AD. Measurements were performed at the corneal vertex and mid-peripheral area. The mid-peripheral corneal thickness was measured at the superior, inferior, nasal, and temporal locations at a distance of 1.0 or 2.5 mm from the corneal vertex. The predicted AD was calculated by ORK-CAM software (Schwind eye tech-solutions GmbH, Kleinostheim, Germany), and the difference between the predicted AD and postop-AD was defined as Δ-AD. Paired t-test analysis was employed to evaluate the differences, agreement was assessed by the Bland-Altman method.ResultsForty-two eyes of 42 patients were investigated. At one month, the predicted AD in the central and paracentral areas was underestimated by the Pentacam HR (Oculus, Wetzlar, Germany), Sirius (Costruzione Strumenti Oftalmici, Florence, Italy) and RTVue OCT (Optovue Inc., Freemont, CA, United States), whereas Δ-AD was negative as established by all devices and predominantly statistically significant. The Δ-AD values approximated zero at three months. The mean difference of Δ-AD at three months at the corneal vertex was 0.67 ± 9.39 mm, −7.92 ± 9.05 mm and −1.36 ± 8.31 mm, respectively. The mid-peripheral measurements had positive values at one month and even more highly positive at three months (with statistically significant differences in most of the cases). The agreement between the predicted and postop-AD was moderate with all devices, but slightly better with RTVue.ConclusionThe predicted AD seems to be underestimated in the central and paracentral corneal area and overestimated in the mid-periphery.Translational RelevanceThe study could help to partly explain and prevent the refractive errors after FS-LASIK.https://www.frontiersin.org/articles/10.3389/fmed.2022.907334/fullablation depthlaser in situ keratomileusisfemtosecond laserdifferenceagreement |
| spellingShingle | Hao Chen Ziqian Wang Kunke Li Yiran Wang Xin Li Lan Du Meimin Lin Giacomo Savini Qinmei Wang Ayong Yu Sisi Chen Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT Frontiers in Medicine ablation depth laser in situ keratomileusis femtosecond laser difference agreement |
| title | Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT |
| title_full | Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT |
| title_fullStr | Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT |
| title_full_unstemmed | Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT |
| title_short | Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT |
| title_sort | agreement between predicted and actual measured ablation depth after fs lasik using different rotating scheimpflug cameras and oct |
| topic | ablation depth laser in situ keratomileusis femtosecond laser difference agreement |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.907334/full |
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