Variable-order sequence modeling improves bacterial strain discrimination for Ion Torrent DNA reads
Abstract Background Genome sequencing provides a powerful tool for pathogen detection and can help resolve outbreaks that pose public safety and health risks. Mapping of DNA reads to genomes plays a fundamental role in this approach, where accurate alignment and classification of sequencing data is...
Main Authors: | Thomas M. Poulsen, Martin Frith |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-06-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-017-1710-0 |
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